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The 10 richest nonprofits in South Carolina

McLeod Regional Medical Center of the Pee Dee Inc is #1 with $2.6 billion in net assets.

#1 · McLeod Regional Medical Center of the Pee Dee Inc
$2.6 billion
All South Carolina nonprofits combined
$45.7 billion
8,916 e-filed returns

The list

Net assets (fund balance) at the end of the year: what the organization owns minus what it owes.

  1. 1McLeod Regional Medical Center of the Pee Dee Inc990, year ended Sep 2025$2.6B
  2. 2Prisma Health990, year ended Sep 2025$2.4B
  3. 3Roper ST Francis Healthcare990, year ended Dec 2024$1.8B
  4. 4Lexington Health Inc990, year ended Sep 2025$1.6B
  5. 5Furman University990, year ended Jun 2025$1.2B
  6. 6Clemson University Foundation990, year ended Jun 2025$1.1B
  7. 7Anmed Health System990, year ended Dec 2024$1.1B
  8. 8Anmed Health990, year ended Dec 2024$1.1B
  9. 9University of South Carolina Educational Foundation990, year ended Jun 2025$821.8M
  10. 10The Medical University of South Carolina Foundation990, year ended Jun 2025$778.8M

More rankings

Richest (net assets) by state