Nonprofit · EIN 45-5312680
LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC
Tax-exempt (reinstated) · FAIRFAX, VA 22030
Financials
| Year ended | Form | Revenue | Expenses | Net income | Total assets | Liabilities | Net assets |
|---|---|---|---|---|---|---|---|
| October 31, 2025 | 990 | $3,614,812 | $3,137,090 | $477,722 | $2,510,395 | $1,553,362 | $957,033 |
| December 31, 2024 | 990 | $4,423,059 | $3,741,763 | $681,296 | $2,422,363 | $1,525,864 | $896,499 |
| December 31, 2023 | 990 | $3,351,390 | $3,676,714 | -$325,324 | $1,851,613 | $960,693 | $890,920 |
| December 31, 2022 | 990 | $3,020,151 | $2,474,219 | $545,932 | $2,144,032 | $920,788 | $1,223,244 |
| December 31, 2021 | 990 | $2,664,551 | $2,093,309 | $571,242 | $1,635,612 | $958,300 | $677,312 |
Financial details: 990 for the year ended October 31, 2025
Revenue
- Contributions, gifts and grants
- $745,413
- Program service revenue
- $2,848,672
- Investment income
- $20,727
- Net gain from sales of assets
- $7,274
- Other revenue
- $0
Expenses
- Grants and similar amounts paid
- $0
- Compensation of officers, directors and key employees
- $606,734
- Other salaries and wages
- $794,257
- Salaries, compensation and benefits (total)
- $1,641,081
- Professional fundraising fees
- $0
- Legal fees
- $53,419
- Accounting fees
- $6,580
- Occupancy
- $166,808
- Travel
- $78,406
- Depreciation
- $21,607
- Program services (functional)
- $2,889,675
- Management and general (functional)
- $243,534
- Fundraising (functional)
- $3,881
Balance sheet and other
- Total assets, start of year
- $2,422,363
- Total assets, end of year
- $2,510,395
- Total liabilities, end of year
- $1,553,362
- Net assets, end of year
- $957,033
- Land, buildings and equipment
- $200,674
- Publicly traded securities
- $1,362,888
- Net assets without donor restrictions
- $957,033
- Gross receipts
- $4,217,542
- Employees
- 0
- Volunteers
- 3
- Year formed
- 2012
- State of legal domicile
- MD
From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.
Officers, directors and key employees
As listed on the 990 for the year ended October 31, 2025, highest compensation first.
| Name | Title | Hours / week | Compensation |
|---|---|---|---|
| DR OZLEM GOKER-ALPAN | PRESIDENT Trustee or director, Officer | 40 | $0 |
| UYENSA BEESE | TREASURER / OPERATIONS DIRECTOR Trustee or director, Officer | 40 | $0 |
| BOBBY SANDHU | SECRETARY / LPN (THRU OCTOBER) Trustee or director, Officer | 40 | $0 |
| LAUREN NOLL | DIRECTOR / MANAGER (THRU OCTOBER) Trustee or director | 40 | $0 |
990 for the year ended December 31, 2024: 5 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| DR OZLEM GOKER-ALPAN | PRESIDENT / FOUNDER Trustee or director, Officer | 40 | $318,291 | $9,018 |
| MARGARITA IVANOVA | DIR. OF TRANSLATIONAL RESEARCH Highest-paid employee | 40 | $135,796 | $0 |
| LAUREN NOLL | DIRECTOR / MANAGER Trustee or director | 40 | $123,056 | $3,964 |
| UYENSA BEESE | TREASURER / OPERATIONS DIRECTOR Trustee or director, Officer | 40 | $110,124 | $5,942 |
| BOBBY SANDHU | SECRETARY / LPN Trustee or director, Officer | 40 | $88,413 | $0 |
990 for the year ended December 31, 2023: 6 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| DR OZLEM GOKER-ALPAN | PRESIDENT / FOUNDER Trustee or director, Officer | 16 | $289,151 | $7,804 |
| MARGARITA IVANOVA | DIR. OF TRANSLATIONAL RESEARCH Highest-paid employee | 40 | $112,241 | $0 |
| LIA H VAN | NURSE PRACTITIONER Highest-paid employee | 40 | $105,715 | $0 |
| LAUREN NOLL | DIRECTOR / MANAGER Trustee or director | 8 | $101,862 | $3,567 |
| UYENSA BEESE | TREASURER / OPERATIONS DIRECTOR Trustee or director, Officer | 24 | $70,458 | $5,299 |
| BOBBY SANDHU | SECRETARY / LPN Trustee or director, Officer | 8 | $73,800 | $0 |
990 for the year ended December 31, 2022: 4 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| DR OZLEM GOKER-ALPAN | PRESIDENT/FOUNDER Trustee or director, Officer | 16 | $296,653 | $8,188 |
| MARGARITA IVANOVA | DIRECTOR Trustee or director | 8 | $100,913 | $0 |
| UYENSA BEESE | TREASURER Trustee or director, Officer | 24 | $66,738 | $5,439 |
| RENUKA LIMGALA | SECRETARY Trustee or director, Officer | 8 | $0 | $0 |
990 for the year ended December 31, 2021: 4 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| DR OZLEM GOKER-ALPAN | PRESIDENT/FOUNDER Trustee or director, Officer | 16 | $345,152 | $35,499 |
| MARGARITA IVANOVA | DIRECTOR Trustee or director | 8 | $93,575 | $0 |
| UYENSA BEESE | TREASURER Trustee or director, Officer | 24 | $64,383 | $24,850 |
| RENUKA LIMGALA | SECRETARY Trustee or director, Officer | 8 | $42,833 | $0 |
Address and contacts
- Address (IRS master file)
- 3702 PENDER DR STE 170, FAIRFAX, VA 22030-6066
- In care of
- % UYEN-SA BEESE
- Mailing address (990-N for 2013)
- 11212 WAPLES MILL ROAD SUITE 100, FAIRFAX VA 22030
- Principal officer (990 for 2025)
- DR OZLEM GOKER-ALPAN, 3702 PENDER DRIVE 170, FAIRFAX, VA 22030
- Principal officer (990-N for 2013)
- UYEN-SA BEESE, 11212 WAPLES MILL ROAD SUITE 100, FAIRFAX VA 22030
- Signed the 990
- UYENSA BEESE, TREASURER/OPERATIONS DIRECTOR
- Phone
- (703) 261-6220
- Website
- LYSOSOMALCENTER.ORG
- Return prepared by
- HAN GROUP LLC
Mission
THE MISSION OF THE LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER (LDRTC) IS TO IMPROVE THE DIAGNOSIS, TREATMENT, AND UNDERSTANDING OF LYSOSOMAL AND OTHER RARE GENETIC DISORDERS BY CONDUCTING SCIENTIFIC RESEARCH, ADVANCING TRANSLATIONAL MEDICINE, EDUCATING HEALTHCARE PROFESSIONALS AND PATIENTS, AND PROMOTING THE DEVELOPMENT OF INNOVATIVE THERAPIES.
Program accomplishments
- INDUSTRY-SPONSORED CLINICAL RESEARCH: LDRTC CONDUCTS INDUSTRY-SPONSORED CLINICAL RESEARCH IN LYSOSOMAL AND OTHER RARE GENETIC DISORDERS, INCLUDING STUDIES OF INVESTIGATIONAL AND APPROVED THERAPIES. THROUGH THESE RESEARCH PROGRAMS, LDRTC PARTICIPATES IN THE SCIENTIFIC AND CLINICAL EVALUATION OF THERAPEUTIC APPROACHES, GENERATES AND CONTRIBUTES CLINICAL RESEARCH DATA, AND SUPPORTS THE DEVELOPMENT AND REGULATORY EVALUATION OF THERAPIES FOR RARE DISEASES. THESE ACTIVITIES ARE CONDUCTED PURSUANT TO CLINICAL RESEARCH AGREEMENTS WITH PHARMACEUTICAL AND BIOTECHNOLOGY SPONSORS AND IN ACCORDANCE WITH APPLICABLE RESEARCH PROTOCOLS AND REGULATORY REQUIREMENTS.INVESTIGATOR-INITIATED RESEARCH: LDRTC INDEPENDENTLY DEVELOPS AND CONDUCTS INVESTIGATOR-INITIATED RESEARCH TO ADVANCE THE UNDERSTANDING OF LYSOSOMAL AND OTHER RARE GENETIC DISORDERS. THESE ACTIVITIES INCLUDE STUDIES OF DISEASE MECHANISMS AND NATURAL HISTORY, BIOMARKER DISCOVERY AND VALIDATION, GENOTYPE-PHENOTYPE RELATIONSHIPS, DISEASE PROGRESSION, CLINICAL OUTCOME MEASURES, AND INNOVATIVE THERAPEUTIC APPROACHES. INVESTIGATOR-INITIATED RESEARCH IS SUPPORTED THROUGH RESEARCH GRANTS AND OTHER CHARITABLE FUNDING, AND FINDINGS ARE DISSEMINATED THROUGH PEER-REVIEWED PUBLICATIONS AND PRESENTATIONS AT NATIONAL AND INTERNATIONAL SCIENTIFIC MEETINGS.Expenses $2,431,567 · revenue $2,793,672
- SCIENTIFIC, PROFESSIONAL, AND PATIENT EDUCATION: LDRTC ADVANCES EDUCATION IN LYSOSOMAL AND OTHER RARE GENETIC DISORDERS THROUGH SCIENTIFIC SYMPOSIA, CONFERENCES, PROFESSIONAL AND CONTINUING MEDICAL EDUCATION, FELLOWSHIP AND HEALTHCARE PROFESSIONAL TRAINING, PATIENT AND CAREGIVER EDUCATION, WORKSHOPS, WEBINARS, AND OTHER COLLABORATIVE EDUCATIONAL INITIATIVES. THESE PROGRAMS ARE DESIGNED TO DISSEMINATE SCIENTIFIC KNOWLEDGE, IMPROVE DISEASE RECOGNITION AND DIAGNOSIS, ADVANCE CLINICAL MANAGEMENT, EDUCATE THE RARE-DISEASE WORKFORCE, AND PROVIDE PATIENTS AND FAMILIES WITH CURRENT INFORMATION ABOUT RARE DISORDERS AND EMERGING THERAPIES.Expenses $458,108 · revenue $55,000
What it must file and when
IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.
| Tax year | Year ended | Due | IRS public records |
|---|---|---|---|
| 2025 | December 31, 2025 | May 15, 2026 | Not on file |
| 2024 | December 31, 2024 | May 15, 2025 | 990 on file |
| 2023 | December 31, 2023 | May 15, 2024 | 990 on file |
IRS record
- EIN
- 45-5312680
- Tax-exempt status
- 501(c)(3): Charitable, religious, educational or scientific organization
- Foundation status
- Publicly supported organization (170(b)(1)(A)(vi))
- Donations deductible (Pub 78)
- Public charity, 50% deduction limit
- Exempt since
- 2021
- Accounting year ends
- December
- Files
- Form 990 or 990-EZ
- Category (NTEE)
- Medical research (H80)
- Assets (IRS master file)
- $2,422,363
- Income (IRS master file)
- $4,423,059
Revocation and reinstatement
- Exemption revoked
- May 15, 2019
- Posted by the IRS
- February 10, 2020
- Reinstated
- Effective May 15, 2019
From the IRS automatic revocation list: organizations that did not file a required return or e-Postcard for three consecutive years.
Filing history
| Form | Year ended | Revenue | Expenses | Assets | Return |
|---|---|---|---|---|---|
| 990 | October 2025 | $3,614,812 | $3,137,090 | $2,510,395 | XML |
| 990 | December 2024 | $4,423,059 | $3,741,763 | $2,422,363 | XML |
| 990 | December 2023 | $3,351,390 | $3,676,714 | $1,851,613 | XML |
| 990 | December 2022 | $3,020,151 | $2,474,219 | $2,144,032 | XML |
| 990 | December 2021 | $2,664,551 | $2,093,309 | $1,635,612 | XML |
| 990 | December 2020 | $1,934,480 | $2,201,912 | $834,123 | IRS |
| 990-N for 2013 Officer: UYEN-SA BEESE | December 31, 2013 | ≤ $50,000 receipts | – | – | e-Postcard |
990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 45-5312680).
Questions about LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC
- What is the EIN of LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC?
- The employer identification number (EIN) of LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC is 45-5312680.
- Is LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC tax-exempt?
- Yes. The IRS revoked its exemption on May 15, 2019 and reinstated it effective May 15, 2019.
- Are donations to LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC tax-deductible?
- Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
- Which annual return does LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC file?
- Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
- When is the next return of LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC due?
- The return for tax year 2025 (the year ending December 31, 2025) is due May 15, 2026. Form 8868 extends it by six months; the 990-N cannot be extended.
- When did LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC last file with the IRS?
- The latest return in the IRS public files is the 990 for the year ended October 2025.
- Who is the principal officer of LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC?
- The 990 for the year ended October 31, 2025 names DR OZLEM GOKER-ALPAN.
- Who are the officers and directors of LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC?
- The 990 for the year ended October 31, 2025 lists 4 people; 0 received compensation from the organization.
- How much revenue does LYSOSOMAL AND RARE DISORDERS RESEARCH AND TREATMENT CENTER INC have?
- On its 990 for the year ended October 31, 2025 it reported revenue of $3,614,812, expenses of $3,137,090 and total assets of $2,510,395 at year end.
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