600 MILLION STRAY DOGS NEED YOU

Financials

From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.

Officers, directors and key employees

As listed on the 990 for the year ended December 31, 2025, highest compensation first.

Address and contacts

Address (IRS master file)

PO BOX 1065, POMPANO BEACH, FL 33061-1065

In care of

% ALEX PACHECO

Mailing address (990-N for 2009)

1000 S Ocean Blvd 9-P, Pompano Beach FL 33062

Principal officer (990 for 2025)

Alexander Pacheco, PO Box 1065, Pompano Beach, FL 33061

Principal officer (990-N for 2009)

Alex Pacheco, 1000 S Ocean Blvd 9-P, Pompano Beach FL 33062

Signed the 990

Alexander Pacheco, President

Phone

(954) 464-9331

Website

www.600milliondogs.org

Return prepared by

Anthony Mansueto CPA

Mission

To end the #1 cause of suffering and death for dogs and cats globally, by developing food that will spay and neuter them, without surgery and end the overpopulation problem without killing. Humane education; fighting to prevent the suffering of children and all animals.

Program accomplishments

• Science Overview for 2025 and the Global Problem We Seek to Solve1) It is believed by many that the global crisis of homeless companion animal overpopulation, the number one cause of suffering for dogs and cats, increased throughout 2025 as their primary source of food increased: human garbage. Millions of homeless dogs and cats continued to suffer as the cycle of reproduction of the homeless by the homeless repeated generation after generation. To end this suffering, our mission remained science-driven and unprecedented: to end the Number One cause of *continued on Sch O *continued from page 2* suffering and premature death for dogs and cats worldwide -overpopulation - by advancing the development of what will become the first one-dose, edible, permanent-lasting birth control formula capable of safely sterilizing stray dogs and cats without surgery.Recognizing that traditional spay and neuter surgery alone cannot solve this problem worldwide, we continued advancing the development of the Spay and Neuter Cookie as a cruelty-free, scalable, science-based, effective alternative. Building upon prior progress, we continued testing chemicals to produce lifelong sterilization from a single cookie, while our small dedicated team continued advancing this groundbreaking and complex scientific work, despite serious constraints ranging from threats and harassment to insufficient resources and funding. 2) In 2025, we were compelled to spend a substantial amount of effort improving the crucial analysis of 'the follicle count'. Before delving into these specifics, it is important to understand why the follicle count is so important.In short, the follicle count tells us whether our birth-control formula is actually working. Follicles are located in the ovaries, and once a follicle dies (usually with advancing age), it cannot be replaced, and without enough follicles, reproduction cannot take place. This natural condition in humans is referred to as menopause. As our goal is to develop a single-dose, permanent, lasting birth control treatment for dogs and cats, the most important question is: Did our formula permanently shut down the ovary's ability to produce future eggs? The follicle count helps answer that question.Before the follicle count: Researchers often had to rely on indirect clues: Did the animal become pregnant? Or did hormone levels change? Any number of questions. The problem is that these clues can be misleading. The follicle count gives us a more direct answer. By carefully examining treated ovarian tissues and analyzing their follicles, we can determine: How many follicles remain. What types of follicles remain? Whether the treatment damaged only some follicles or nearly all of them, and so on.Why this matters: We are not trying to create a birth control method that works for a few months. We are working to develop something far more ambitious: A safe, inexpensive, edible, one-dose treatment that permanently prevents reproduction - without the need for capture, injections or surgery. To prove that such a treatment truly works, we need evidence that the formula has eliminated, or sufficiently depleted, the viable ovarian reserve. The follicle count is one of the strongest ways to demonstrate that. A robust follicle-count method can help answer questions from: Scientific reviewers, Grant agencies, Regulatory authorities, Veterinary experts, and Potential partners. It provides objective evidence rather than relying on assumptionsIn short: The follicle count is important because it allows us to directly measure whether our one-dose formula has permanently disabled the ovary's capacity to produce fertile eggs that are necessary for becoming pregnant - the central requirement for ending the uncontrolled reproduction in stray dogs and cats.3) Analyzing the Follicle: Our Attempts to Automate Pathology Reporting with Artificial Intelligence. In 2025 we invested significant time in attempting to automate our pathology reporting using AI, hoping to speed up the expensive, labor-intensive work of evaluating follicles digital slide by digital slide. Unfortunately, this effort was not successful. AI-based classification and analysis is simply not good enough yet to meet our needs. Unfortunately it does not yet meet the level of accuracy that our work demands. In short, the variability and subtlety that we require, in follicle detection and staging, continued to exceed what current automated tools could/can reliably handle. While the experiments did not deliver the time savings we had hoped for, they clarified where automation can and cannot yet be trusted, and it reinforced why our rigorous, human-led pathology, and tools like our follicle quiz, remain essential. 4) To deal with this important problem, we developed the follicle quiz pipeline - the follicle quiz for short. Much effort had to be invested in developing the follicle quiz. The need for it grew directly out of a problem we kept running into: we observed real variability and differences in follicle detection and classification - across different veterinary pathologists, and there was no easy way to understand or quantify or localize where those disagreements were coming from or what they were based on. As the accuracy of each formula depends on how reliably follicles are counted and staged, this kind of variation is not something we could, nor can, afford to leave unresolved. Static annotations and side discussions were and are, not enough. We needed a way to directly visualize and compare how different pathologists were interpreting the same raw material: treated follicles. This is why we had to build a structured comparison tool ourselves.Although the result appears to be a single, rather simple yet highly structured product, in the form of an online platform, getting there required a deeply involved process, requiring several structured, interconnected steps. We first evaluated annotation software such as ImageScope and QuPath, and after careful testing and comparison we found QuPath to be more suitable and easier to build a workflow around, and therefore decided to proceed with it. We then turned to image extraction and processing: to enable analysis at the level of individual follicles, one by one in a format easy for both pathologists and non-pathologists to work with. To accomplish this we also needed to convert each annotated follicle into a standalone image, which required developing a pipeline to extract annotated regions (of digital histological slides of our treated ovaries) from whole-slide images and save them as individual online files. Finally, we built the follicle quiz platform itself, both frontend and backend interactively refining it for functionality and usability, integrating the image processing pipeline with the quiz system, and carrying out multiple rounds of testing to ensure correctness, stability, and reliability. In other words we built an online platform that allows multiple pathologists to all examine the same 100 to 1,000 treated follicles, at the same time, and analyze each follicle at the same time, in a user friendly much more time efficient manner than ever before, and ultimately, deliver the combined data to us in format that makes it much easier to compare and understand the analysis by each pathologist individually and as a group. 5) Digital Slide Quality and Proper Ovarian Histology: We discovered that not all of the digital slides were quite up to standard, and we decided to search for companies capable of preparing them at the highest level. Slide quality is not a minor detail, it determines whether our follicle counts are meaningful. To properly evaluate the treated ovary, the objective is to obtain a true cross-section that includes all key anatomical components, and in their correct spatial relationship. The follicles themselves are stratified by developmental stage: for example, the most immature primordial and primary follicles are typically clustered in the outermost region of the cortex, just deep to the capsule, while secondary and tertiary follicles are found deeper within the cortex as they mature. To continue to accurately assess the follicular population, for example for follicular counts or staging , the histological slide must represent this complete architecture. We spent considerable time getting this right, because without it, even a perfectly designed formula may not be reliably evaluated, which of course is unacceptable. 6) As to be expected, we encountered some related problems which we also had to resolve, for example in the case of Pilot Pup Allie. Her treated tissue on the slide was problematic because the section appeared to miss or underrepresent the follicle-bearing cortical region, possibly due to tissue orientation within the cassette or sectioning near the pole of the ovary. We deemed the slide as essentially non-diagnostic for our follicular analysis
  Expenses $407,478

What it must file and when

IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.

IRS record

EIN

33-0601340

Tax-exempt status

501(c)(3): Charitable, religious, educational or scientific organization

Foundation status

Publicly supported organization (509(a)(2))

Donations deductible (Pub 78)

Public charity, 50% deduction limit

Exempt since

1998

Accounting year ends

December

Files

Form 990 or 990-EZ

Category (NTEE)

Animal-related (D20)

Assets (IRS master file)

$1,116,991

Income (IRS master file)

$711,807

Filing history

990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 33-0601340).

Questions about 600 MILLION STRAY DOGS NEED YOU

What is the EIN of 600 MILLION STRAY DOGS NEED YOU?

The employer identification number (EIN) of 600 MILLION STRAY DOGS NEED YOU is 33-0601340.

Is 600 MILLION STRAY DOGS NEED YOU tax-exempt?

Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 1998.

Are donations to 600 MILLION STRAY DOGS NEED YOU tax-deductible?

Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).

Which annual return does 600 MILLION STRAY DOGS NEED YOU file?

Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.

When is the next return of 600 MILLION STRAY DOGS NEED YOU due?

The return for tax year 2026 (the year ending December 31, 2026) is due May 17, 2027. Form 8868 extends it by six months; the 990-N cannot be extended.

When did 600 MILLION STRAY DOGS NEED YOU last file with the IRS?

The latest return in the IRS public files is the 990 for the year ended December 2025.

Who is the principal officer of 600 MILLION STRAY DOGS NEED YOU?

The 990 for the year ended December 31, 2025 names Alexander Pacheco.

Who are the officers and directors of 600 MILLION STRAY DOGS NEED YOU?

The 990 for the year ended December 31, 2025 lists 3 people; 1 received compensation from the organization, the highest $43,030 (Alexander Pacheco, CEO, President).

How much revenue does 600 MILLION STRAY DOGS NEED YOU have?

On its 990 for the year ended December 31, 2025 it reported revenue of $711,807, expenses of $494,330 and total assets of $1,116,991 at year end.

Other nonprofits in POMPANO BEACH

• EVERGLADES ANGELS DOG RESCUE INC
  EIN 46-4812463 · last filed 990 for 2025
• THE FLORIDA HUMANE SOCIETY INC
  EIN 65-0409889 · last filed 990 for 2024
• LADY LUCK ANIMAL RESCUE INC
  EIN 27-2635336 · last filed 990 for 2024
• BEYOND NINE CAT RESCUE INC
  EIN 20-8883605 · last filed 990-EZ for 2024
• GRAY FISHTAG RESEARCH INC
  EIN 47-2063764 · last filed 990-EZ for 2024
• BLUE WATERS DOG RESCUE
  EIN 81-3752060 · last filed 990-EZ for 2025
• SOUTHFLORIDACATSANDKITTENS
  EIN 99-0731582 · last filed 990-N for 2025
• CAT TALES FROM THE STREETS
  EIN 93-2043728 · last filed 990-N for 2024

All nonprofits in POMPANO BEACH · Florida · Animal-related