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Nonprofit · EIN 52-2029668

INSTITUTE FOR IN VITRO SCIENCES INC

Tax-exempt · GAITHERSBURG, MD 20878

Financials

$6.9M$7.2M2023$8M$7.9M2024$7.9M$7.9M2025
Revenue Expenses · by fiscal year end
Financials of INSTITUTE FOR IN VITRO SCIENCES INC by year, from its e-filed returns
Year endedFormRevenueExpensesNet incomeTotal assetsLiabilitiesNet assets
December 31, 2025990$7,901,249$7,883,164$18,085$5,555,372$3,178,014$2,377,358
December 31, 2024990$7,953,184$7,935,798$17,386$5,925,753$3,566,480$2,359,273
December 31, 2023990$6,877,981$7,165,636-$287,655$6,152,852$3,810,965$2,341,887
Financial details: 990 for the year ended December 31, 2025

Revenue

Contributions, gifts and grants
$793,498
of which government grants
$38,826
Program service revenue
$7,069,056
Investment income
$5,626
Other revenue
$33,069

Expenses

Grants and similar amounts paid
$0
Compensation of officers, directors and key employees
$354,961
Other salaries and wages
$3,454,068
Salaries, compensation and benefits (total)
$4,555,039
Professional fundraising fees
$0
Legal fees
$7,215
Accounting fees
$58,919
Occupancy
$546,566
Travel
$169,703
Depreciation
$234,005
Program services (functional)
$7,399,857
Management and general (functional)
$462,888
Fundraising (functional)
$20,419

Balance sheet and other

Total assets, start of year
$5,925,753
Total assets, end of year
$5,555,372
Total liabilities, end of year
$3,178,014
Net assets, end of year
$2,377,358
Land, buildings and equipment
$712,291
Net assets without donor restrictions
$2,333,200
Net assets with donor restrictions
$44,158
Gross receipts
$7,901,249
Employees
56
Volunteers
5
Year formed
1997
State of legal domicile
MD

From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.

Officers, directors and key employees

As listed on the 990 for the year ended December 31, 2025, highest compensation first.

NameTitleHours / weekCompensationOther / benefits
HOLGER P BEHRSINGDIRECTOR RESPIRATORY TOXICOLOGY
Highest-paid employee
40$165,396$15,866
HANS A RAABECHIEF OPERATING OFFICER/TREASURER
Trustee or director, Officer
40$152,576$20,220
AMANDA K ULREYPRESIDENT
Trustee or director, Officer
40$160,387$7,410
GERTRUDE-EMILIA COSTINDIRECTOR OF LABORATORY SERVICES
Highest-paid employee
40$153,460$12,083
ALLISON M HILBERERTOXICOLOGIST II/STUDY DIRECTOR
Highest-paid employee
40$123,067$13,770
NATHAN R WILTSTUDY DIRECTOR
Highest-paid employee
40$121,135$13,974
KRISTIE M SULLIVANVP, EDUCATION AND OUTREACH
Highest-paid employee
40$117,318$5,737
RODGER D CURRENCEO/BOARD CHAIR/SECRETARY
Trustee or director, Officer
10$13,815$553
DANIEL A BAGLEYDIRECTOR
Trustee or director
0.5$0$0
JOHN R FOWLEDIRECTOR
Trustee or director
0.5$0$0
A WALLACE HAYESDIRECTOR
Trustee or director
0.5$0$0
JAMES M HOFFMANDIRECTOR
Trustee or director
0.5$0$0
RICHARD E KOURIDIRECTOR
Trustee or director
0.5$0$0
990 for the year ended December 31, 2024: 13 people
NameTitleHours / weekCompensationOther / benefits
HOLGER P BEHRSINGDIRECTOR RESPIRATORY TOXICOLOGY
Highest-paid employee
40$161,185$14,748
HANS A RAABECHIEF OPERATING OFFICER/TREASURER
Trustee or director, Officer
40$148,071$17,733
AMANDA K ULREYPRESIDENT
Trustee or director, Officer
40$155,148$8,722
GERTRUDE-EMILIA COSTINDIRECTOR OF LABORATORY SERVICES
Highest-paid employee
40$150,051$11,298
ALLISON M HILBERERTOXICOLOGIST II/STUDY DIRECTOR
Highest-paid employee
40$120,182$13,112
NATHAN R WILTSTUDY DIRECTOR
Highest-paid employee
40$118,662$13,305
KRISTIE M SULLIVANVP, EDUCATION AND OUTREACH
Highest-paid employee
40$114,604$6,845
RODGER D CURRENCEO/BOARD CHAIR/SECRETARY
Trustee or director, Officer
10$20,962$838
DANIEL A BAGLEYDIRECTOR
Trustee or director
0.5$0$0
JOHN R FOWLEDIRECTOR
Trustee or director
0.5$0$0
A WALLACE HAYESDIRECTOR
Trustee or director
0.5$0$0
JAMES M HOFFMANDIRECTOR
Trustee or director
0.5$0$0
RICHARD E KOURIDIRECTOR
Trustee or director
0.5$0$0
990 for the year ended December 31, 2023: 14 people
NameTitleHours / weekCompensationOther / benefits
HANS A RAABECHIEF OPERATING OFFICER/TREASURER
Trustee or director, Officer
40$153,112$25,023
HOLGER P BEHRSINGDIRECTOR RESPIRATORY TOXICOLOGY
Highest-paid employee
40$156,494$14,731
GERTRUDE-EMILIA COSTINDIRECTOR OF LABORATORY SERVICES
Highest-paid employee
40$145,496$23,064
BRENT J GILBERTDIRECTOR, BUSINESS DEVELOPMENT
Highest-paid employee
40$142,627$25,692
AMANDA K ULREYPRESIDENT/BOARD MEMBER
Trustee or director, Officer
40$138,367$6,590
QUANSHUN ZHANGSENIOR SCIENTIST & PROJECT LEADER
Highest-paid employee
40$106,201$28,231
NATHAN R WILTSTUDY DIRECTOR
Highest-paid employee
40$114,995$16,432
RODGER D CURRENCEO/BOARD CHAIR/SECRETARY
Trustee or director, Officer
10$51,077$1,071
ERIN H HILLPRESIDENT/BOARD MBR. (THRU 1/2023)
Trustee or director, Officer
40$15,575$1,294
JOHN R FOWLEDIRECTOR
Trustee or director
0.5$0$0
JAMES M HOFFMANDIRECTOR
Trustee or director
0.5$0$0
RICHARD E KOURIDIRECTOR
Trustee or director
0.5$0$0
A WALLACE HAYESDIRECTOR
Trustee or director
0.5$0$0
DANIEL A BAGLEYDIRECTOR
Trustee or director
0.5$0$0

Address and contacts

Address (IRS master file)
30 W WATKINS MILL RD STE 100, GAITHERSBURG, MD 20878-4005
Principal officer (990 for 2025)
AMANDA K ULREY, 30 W WATKINS MILL ROAD 100, GAITHERSBURG, MD 20878
Signed the 990
AMANDA K ULREY, PRESIDENT
Phone
(301) 947-6523
Website
IIVS.ORG
Return prepared by
HAN GROUP LLC

Mission

THE MISSION OF THE INSTITUTE FOR IN VITRO SCIENCES (IIVS) IS TO DRIVE THE OPTIMIZATION AND APPLICATION OF SCIENTIFICALLY ROBUST IN VITRO METHODS THAT ARE ACCEPTED BY REGULATORY AGENCIES AND ADOPTED BY INDUSTRY WORLDWIDE. TO CREATE A FORUM IN WHICH INDUSTRY, REGULATORY AGENCIES AND ANIMAL WELFARE ORGANIZATIONS CAN WORK TOGETHER TO DEVELOP HUMANE SCIENTIFIC TOOLS FOR TESTING. TO UTILIZE OUR EXPERTISE TO CREATE EDUCATIONAL AND OUTREACH PROGRAMS THAT WILL EXPAND THE ADOPTION OF NON-ANIMAL TEST METHODS AROUND THE GLOBE.

990 for the year ended December 31, 2025

Program accomplishments

  • RESEARCH AND TESTING: IIVS WORKED WITH MORE THAN SIXTY COMPANIES TO DETERMINE THE APPROPRIATE NON-ANIMAL TESTING STRATEGIES, CONDUCT TESTING, AND ASSIST IN INTERPRETATION OF DATA. OVER 880 COMPOUNDS/PRODUCTS WERE TESTED AT THE IIVS LABORATORY - MOSTLY IN MORE THAN ONE TEST. IIVS CONTINUES TO OPTIMIZE AND STANDARDIZE IN VITRO METHODS TO MAKE THEM SUITABLE FOR INDUSTRY AND REGULATORY NEEDS. MANY OF THESE EFFORTS ARE IN COLLABORATION WITH STAKEHOLDERS SUCH AS INDUSTRY, GOVERNMENT AND NGOS. ADVANCEMENTS ARE SHARED WITH THE SCIENTIFIC COMMUNITY THROUGH PRESENTATIONS AND PUBLICATIONS SO THAT OTHER INDUSTRIES AND REGULATORY SCIENTISTS CAN BENEFIT. IIVS HAS DEVELOPED AND PROMOTED THE USE OF HUMAN PRECISION CUT LUNG SLICES (HPCLS) FOR POTENTIAL REGULATORY APPLICATION AS AN ALTERNATIVE TO USING ANIMALS FOR INHALATION AND RESPIRATORY ENDPOINTS. BASED UPON OUR SUCCESSFUL USE OF HPCLS IN IN-HOUSE STUDIES, STAKEHOLDERS HAVE INQUIRED WHETHER THEY COULD PROCURE THESE HPCLS TISSUES FOR USE WITHIN THEIR OWN LABORATORIES. IIVS PREPARED AND QUALIFIED HPCLS TISSUES FOR 30 SPONSOR-RUN LABORATORY STUDIES THAT WOULD HAVE OTHERWISE USED ANIMALS.
    Expenses $6,332,999 · revenue $6,805,283
  • EDUCATION AND OUTREACH: IIVS PARTICIPATES IN NUMEROUS TRAINING ACTIVITIES FOR A VARIETY OF STAKEHOLDERS INCLUDING INDUSTRY AND REGULATORY SCIENTISTS. THESE TRAININGS ARE TAILORED FOR THE SPECIFIC AUDIENCE AND GENERALLY INCLUDE LECTURES, HANDS-ON DEMONSTRATIONS AND DATA INTERPRETATION. TWO MAJOR PROGRAMS IN WHICH IIVS PARTICIPATES ARE THE PHYSICIANS COMMITTEE FOR RESPONSIBLE MEDICINE NURA TRAINING AND THE ANIMAL FREE SAFETY ASSESSMENT COLLABORATION COORDINATED BY HUMANE SOCIETY INTERNATIONAL. IIVS SCIENTISTS WERE INVITED TO PARTICIPATE IN EXPERT PANELS CONVENED BY THE ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT (OECD) WHICH HARMONIZES IN VITRO TESTING APPROACHES FOR THE WORLDWIDE SCIENTIFIC COMMUNITY. THESE PANELS DISCUSSED NEW METHODS FOR GENETIC TOXICOLOGY, SKIN SENSITIZATION, EYE IRRITATION AND SKIN CORROSION. IIVS IS LEADING EFFORTS WITH INDUSTRY CONSORTIA AND 2 DIVISIONS OF THE U.S. FEDERAL DRUG ADMINISTRATION TO APPLY NON-ANIMAL METHODS FOR SPECIFIC ENDPOINTS. IIVS IS ALSO INVOLVED IN EFFORTS TO SUPPORT THE U.S. ENVIRONMENTAL PROTECTION AGENCY'S GOAL TO REDUCE RELIANCE ON ANIMAL MODELS. IIVS STAFF HOLD BOARD POSITIONS WITHIN SOCIETIES THAT HAVE THE MISSION TO WORK COLLABORATIVELY TO INCREASE THE USE AND ACCEPTANCE OF ALTERNATIVE METHODS, SUCH AS THE AMERICAN SOCIETY FOR CELLULAR AND COMPUTATIONAL TOXICOLOGY, THE EUROPEAN SOCIETY OF TOXICOLOGY IN VITRO, THE U.S. SOCIETY OF TOXICOLOGY AND THE CHINESE SOCIETY OF TOXICOLOGY.
    Expenses $1,066,858 · revenue $263,773

What it must file and when

IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.

Tax yearYear endedDueIRS public records
2025December 31, 2025May 15, 2026990 on file
2024December 31, 2024May 15, 2025990 on file
2023December 31, 2023May 15, 2024990 on file

IRS record

EIN
52-2029668
Tax-exempt status
501(c)(3): Charitable, religious, educational or scientific organization
Foundation status
Publicly supported organization (170(b)(1)(A)(vi))
Donations deductible (Pub 78)
Public charity, 50% deduction limit
Exempt since
1997
Accounting year ends
December
Files
Form 990 or 990-EZ
Category (NTEE)
Education (B28)
Assets (IRS master file)
$5,555,372
Income (IRS master file)
$7,901,249

Filing history

FormYear endedRevenueExpensesAssetsReturn
990December 2025$7,901,249$7,883,164$5,555,372XML
990December 2024$7,953,184$7,935,798$5,925,753XML
990December 2023$6,877,981$7,165,636$6,152,852XML
990December 2022$6,860,766$6,922,486$6,566,155IRS
990December 2021–––IRS
990December 2020–––IRS
990December 2018–––IRS

990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 52-2029668).

Questions about INSTITUTE FOR IN VITRO SCIENCES INC

What is the EIN of INSTITUTE FOR IN VITRO SCIENCES INC?
The employer identification number (EIN) of INSTITUTE FOR IN VITRO SCIENCES INC is 52-2029668.
Is INSTITUTE FOR IN VITRO SCIENCES INC tax-exempt?
Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 1997.
Are donations to INSTITUTE FOR IN VITRO SCIENCES INC tax-deductible?
Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
Which annual return does INSTITUTE FOR IN VITRO SCIENCES INC file?
Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
When is the next return of INSTITUTE FOR IN VITRO SCIENCES INC due?
The return for tax year 2026 (the year ending December 31, 2026) is due May 17, 2027. Form 8868 extends it by six months; the 990-N cannot be extended.
When did INSTITUTE FOR IN VITRO SCIENCES INC last file with the IRS?
The latest return in the IRS public files is the 990 for the year ended December 2025.
Who is the principal officer of INSTITUTE FOR IN VITRO SCIENCES INC?
The 990 for the year ended December 31, 2025 names AMANDA K ULREY.
Who are the officers and directors of INSTITUTE FOR IN VITRO SCIENCES INC?
The 990 for the year ended December 31, 2025 lists 13 people; 8 received compensation from the organization, the highest $165,396 (HOLGER P BEHRSING, DIRECTOR RESPIRATORY TOXICOLOGY).
How much revenue does INSTITUTE FOR IN VITRO SCIENCES INC have?
On its 990 for the year ended December 31, 2025 it reported revenue of $7,901,249, expenses of $7,883,164 and total assets of $5,555,372 at year end.

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