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Nonprofit · EIN 47-3425850

CANCER PREVENTION INITIATIVE INC

Also known as HERITX

Tax-exempt · DALLAS, TX 75201

Financials

$50K$74K2023$1.7M$704K2024$779K$857K2025
Revenue Expenses · by fiscal year end
Financials of CANCER PREVENTION INITIATIVE INC by year, from its e-filed returns
Year endedFormRevenueExpensesNet incomeTotal assetsLiabilitiesNet assets
December 31, 2025990$778,663$856,539-$77,876$1,927,394$360,200$1,567,194
December 31, 2024990$1,673,681$703,827$969,854$2,225,249$580,179$1,645,070
December 31, 2023990$49,585$74,394-$24,809$821,212$145,996$675,216
Financial details: 990 for the year ended December 31, 2025

Revenue

Contributions, gifts and grants
$701,483
Program service revenue
$0
Investment income
$77,180
Other revenue
$0

Expenses

Grants and similar amounts paid
$725,000
Compensation of officers, directors and key employees
$0
Salaries, compensation and benefits (total)
$0
Professional fundraising fees
$90,000
Accounting fees
$12,310
Depreciation
$1,600
Program services (functional)
$731,546
Management and general (functional)
$28,204
Fundraising (functional)
$96,789

Balance sheet and other

Total assets, start of year
$2,225,249
Total assets, end of year
$1,927,394
Total liabilities, end of year
$360,200
Net assets, end of year
$1,567,194
Publicly traded securities
$1,855,633
Net assets without donor restrictions
$535,694
Net assets with donor restrictions
$1,031,500
Gross receipts
$778,663
Employees
0
Volunteers
5
Year formed
2015
State of legal domicile
DE

From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.

Officers, directors and key employees

As listed on the 990 for the year ended December 31, 2025, highest compensation first.

NameTitleHours / weekCompensation
Theodora RossPresident & Chief Scientific Officer; Trustee
Trustee or director, Officer
5$0
Howard JanzenBoard Chair; Secretary; Trustee
Trustee or director, Officer
5$0
Jan Livingston-MokhtariTrustee
Trustee or director
1$0
Douglas HagerTrustee, Sr. Vice President, Project Management and Operations
Trustee or director
10$0
Joi MorrisTreasurer, Trustee
Trustee or director, Officer
6$0
Kirk PatrickSecretary, Trustee
Trustee or director
0.5$0
990 for the year ended December 31, 2024: 6 people
NameTitleHours / weekCompensation
Theodora RossPresident & Chief Scientific Officer
Trustee or director, Officer
5$0
Howard JanzenBoard Chair; Chief Financial Officer
Trustee or director, Officer
5$0
Kirk PatrickSecretary, Trustee
Trustee or director, Officer
0.5$0
Jan Livingston-MokhtariTrustee
Trustee or director
0.5$0
Douglas HagerTrustee, Sr. Vice President, Project Management and Operations
Trustee or director
10$0
Joi MorrisTrustee
Trustee or director
5$0
990 for the year ended December 31, 2023: 6 people
NameTitleHours / weekCompensation
Theodora RossPresident & Chief Scientific Officer
Trustee or director, Officer
10$0
Howard JanzenBoard Chair; Chief Financial Officer
Trustee or director, Officer
3$0
Kirk PatrickSecretary, Trustee
Trustee or director, Officer
0.5$0
Jan Livingston-MokhtariTrustee
Trustee or director
0.5$0
Douglas HagerTrustee, Sr. Vice President, Project Management and Operations
Trustee or director
10$0
Joi MorrisTrustee
Trustee or director
5$0

Address and contacts

Address (IRS master file)
1722 ROUTH ST STE 770, DALLAS, TX 75201-2588
In care of
% JOI MORRIS ESQ
Principal officer (990 for 2025)
Theodora Ross, 1722 Routh Street, Suite 770, Dallas, TX 75201
Signed the 990
Theodora Ross, President
Phone
(844) 437-4891

Mission

Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer. CPI uses its research, medical and pharmaceutical expertise to invest in first-rate science that will discover new medical methods for preventing cancer. Our strategy is to support research on prevention of inherited cancers as a path towards elimination of all cancers. CPI acts as a facilitator to ensure that good ideas can find sufficient funding to turn them into therapeutic solutions such as drugs or vaccines to prevent cancer. CPI provides financial support, guidance and expertise throughout the research and development process to help researchers use the resources (donations) for the highest possible impact.

990 for the year ended December 31, 2025

Program accomplishments

  • In 2025, Cancer Prevention Initiative (CPI) supported five active projects studying therapeutic prevention of inherited cancer. Four of the projects study BRCA1/2 mutated cancers and one project studies Lynch Syndrome. Two of the projects, one at Cleveland Clinic and one at Dana-Farber, are developing immunoprevention strategies to combat BRCA mutant breast cancer. Another immunoprevention project at MD Anderson is developing vaccines to prevent Lynch syndrome-associated colorectal cancer. The project at Harvard/Beth Israel Deaconess Medical center is identifying risk factors in the fallopian tube that gives rise to ovarian cancer in BRCA1 mutation carriers. This work would help develop tests and assays for early detection and risk assessment of ovarian cancer. At Memorial Sloan Kettering Cancer Center, CPI supports a project to prevent Loss of Heterozygosity (LoH) of BRCA genes, a major driver in cancer initiation, and thereby prevent the development of cancer.
    Expenses $731,546 · grants $725,000
  • Education and engagement programs: As we move closer to our goal of eradicating all cancers through preventative medicines, we believe that raising awareness about inherited cancer syndromes will inspire more individuals to take proactive, life-saving preventive measures. One of the goals is to enhance the scientific reach of the organization and raise awareness on cancer prevention to a broader audience of patients, advocates and donors. Updates on scientific and medical research advances, recent clinical trials, and interviews with experts in cancer prevention are published on web-based platforms.0

What it must file and when

IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.

Tax yearYear endedDueIRS public records
2025December 31, 2025May 15, 2026990 on file
2024December 31, 2024May 15, 2025990 on file
2023December 31, 2023May 15, 2024990 on file

IRS record

EIN
47-3425850
Tax-exempt status
501(c)(3): Charitable, religious, educational or scientific organization
Foundation status
Publicly supported organization (170(b)(1)(A)(vi))
Donations deductible (Pub 78)
Public charity, 50% deduction limit
Exempt since
2015
Accounting year ends
December
Files
Form 990 or 990-EZ
Category (NTEE)
Medical research (H30)
Assets (IRS master file)
$1,927,394
Income (IRS master file)
$778,663

Filing history

FormYear endedRevenueExpensesAssetsReturn
990December 2025$778,663$856,539$1,927,394IRS
990December 2024$1,673,681$703,827$2,225,249IRS
990December 2023$49,585$74,394$821,212XML
990December 2022$257,068$18,418$1,056,196IRS
990December 2021–––IRS
990December 2020–––IRS
990December 2018–––IRS

990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 47-3425850).

Questions about CANCER PREVENTION INITIATIVE INC

What is the EIN of CANCER PREVENTION INITIATIVE INC?
The employer identification number (EIN) of CANCER PREVENTION INITIATIVE INC is 47-3425850.
Is CANCER PREVENTION INITIATIVE INC tax-exempt?
Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 2015.
Are donations to CANCER PREVENTION INITIATIVE INC tax-deductible?
Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
Which annual return does CANCER PREVENTION INITIATIVE INC file?
Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
When is the next return of CANCER PREVENTION INITIATIVE INC due?
The return for tax year 2026 (the year ending December 31, 2026) is due May 17, 2027. Form 8868 extends it by six months; the 990-N cannot be extended.
When did CANCER PREVENTION INITIATIVE INC last file with the IRS?
The latest return in the IRS public files is the 990 for the year ended December 2025.
Who is the principal officer of CANCER PREVENTION INITIATIVE INC?
The 990 for the year ended December 31, 2025 names Theodora Ross.
Who are the officers and directors of CANCER PREVENTION INITIATIVE INC?
The 990 for the year ended December 31, 2025 lists 6 people; 0 received compensation from the organization.
How much revenue does CANCER PREVENTION INITIATIVE INC have?
On its 990 for the year ended December 31, 2025 it reported revenue of $778,663, expenses of $856,539 and total assets of $1,927,394 at year end.

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