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Nonprofit · EIN 20-1624945

XENOBE RESEARCH INSTITUTE

Tax-exempt · SAN DIEGO, CA 92163

Financials

$175K$132K2024
Revenue Expenses · by fiscal year end
Financials of XENOBE RESEARCH INSTITUTE by year, from its e-filed returns
Year endedFormRevenueExpensesNet incomeTotal assetsLiabilitiesNet assets
June 30, 2025990$174,939$131,801$43,138$271,239$0$271,239
Financial details: 990 for the year ended June 30, 2025

Revenue

Contributions, gifts and grants
$174,939
of which government grants
$147,950
Program service revenue
$0
Investment income
$0
Other revenue
$0

Expenses

Grants and similar amounts paid
$0
Compensation of officers, directors and key employees
$44,352
Salaries, compensation and benefits (total)
$66,600
Professional fundraising fees
$0
Travel
$14,728
Program services (functional)
$131,801

Balance sheet and other

Total assets, start of year
$228,101
Total assets, end of year
$271,239
Total liabilities, end of year
$0
Net assets, end of year
$271,239
Net assets without donor restrictions
$271,239
Gross receipts
$174,939
Employees
1
Volunteers
0
Year formed
2004
State of legal domicile
CA

From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.

Officers, directors and key employees

As listed on the 990 for the year ended June 30, 2025, highest compensation first.

NameTitleHours / weekCompensation
James J La ClairPresident
Trustee or director, Officer, Key employee
10$44,352
Manfred AuerDirector
Trustee or director
5$0

Address and contacts

Address (IRS master file)
PO BOX 3052, SAN DIEGO, CA 92163-1052
In care of
% JAMES LA CLAIR
Principal officer (990 for 2024)
James J La Clair, 10630 Queen Avenue, La Mesa, CA 91941
Signed the 990
James La Clair, President
Phone
(858) 401-3083

Mission

The Xenobe Research Institute conducts research on natural and synthetic small molecule therapeutics with the ultimate goal of discovering and ultimately translating new materials for clinical trials. Funds were obtained from two projects one supported by the NIH and the other by Terra Bioworks

990 for the year ended June 30, 2025

Program accomplishments

  • National Institutes of Health Grant R21NS128597. While well established as clinical targets, the lack of molecular probes to the large immunophilins continues to inhibit our ability to evaluate and drug them clinically. This program explores the development of a general platform to discover probes that target specific domains within a neurological protein. Using cyclophilin 40 (Cyp40), FK506-binding proteins FKBP51 and FKBP52, our team seeks to define critically needed reagents to understand the role of the `large immunophilin' family in neurological disease. We began studies on our recently funded R21 program and have reported signficance success within our initial year of funding.The revenue generated will be used for the latter half of the program. A two year award was provided within this funding period. These funds to cover salaries, research supplies, instrument time, and equipment access to complete these studies.
    Expenses $104,912 · grants $147,950 · revenue $43,407
  • Terra Bioworks. Granted funding was provided to support small molecule isolation and structure elucidation efforts. These funds were used to cover research supplies, instrument time, and equipment access to complete these studies.
    Expenses $26,889 · grants $26,989 · revenue $100
  • None0

What it must file and when

IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in June, so each return is due on the 15th day of the 5th month after that.

Tax yearYear endedDueIRS public records
2025June 30, 2026November 16, 2026Not due yet
2024June 30, 2025November 17, 2025990 on file
2023June 30, 2024November 15, 2024990 on file

IRS record

EIN
20-1624945
Tax-exempt status
501(c)(3): Charitable, religious, educational or scientific organization
Foundation status
Publicly supported organization (170(b)(1)(A)(vi))
Donations deductible (Pub 78)
Public charity, 50% deduction limit
Exempt since
2005
Accounting year ends
June
Files
Form 990 or 990-EZ
Assets (IRS master file)
$271,239
Income (IRS master file)
$174,939

Filing history

FormYear endedRevenueExpensesAssetsReturn
990June 2025–––IRS
990June 2024$61,315$147,500$228,101IRS
990June 2023$352,250$154,772$314,286IRS
990-EZJune 2022–––IRS

990-N: the IRS publishes only the latest e-Postcard per organization; earlier years appear here as 990.tax collects the monthly files. 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS.

Questions about XENOBE RESEARCH INSTITUTE

What is the EIN of XENOBE RESEARCH INSTITUTE?
The employer identification number (EIN) of XENOBE RESEARCH INSTITUTE is 20-1624945.
Is XENOBE RESEARCH INSTITUTE tax-exempt?
Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 2005.
Are donations to XENOBE RESEARCH INSTITUTE tax-deductible?
Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
Which annual return does XENOBE RESEARCH INSTITUTE file?
Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
When is the next return of XENOBE RESEARCH INSTITUTE due?
The return for tax year 2025 (the year ending June 30, 2026) is due November 16, 2026. Form 8868 extends it by six months; the 990-N cannot be extended.
When did XENOBE RESEARCH INSTITUTE last file with the IRS?
The latest return in the IRS public files is the 990 for the year ended June 2025.
Who is the principal officer of XENOBE RESEARCH INSTITUTE?
The 990 for the year ended June 30, 2025 names James J La Clair.
Who are the officers and directors of XENOBE RESEARCH INSTITUTE?
The 990 for the year ended June 30, 2025 lists 2 people; 1 received compensation from the organization, the highest $44,352 (James J La Clair, President).
How much revenue does XENOBE RESEARCH INSTITUTE have?
On its 990 for the year ended June 30, 2025 it reported revenue of $174,939, expenses of $131,801 and total assets of $271,239 at year end.

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