Nonprofit · EIN 13-4043587
NEW YORK STRUCTURAL BIOLOGY CENTER INC
Tax-exempt · NEW YORK, NY 10027
Financials
| Year ended | Form | Revenue | Expenses | Net income | Total assets | Liabilities | Net assets |
|---|---|---|---|---|---|---|---|
| December 31, 2024 | 990 | $19,952,697 | $28,453,802 | -$8,501,105 | $133,938,928 | $11,192,289 | $122,746,639 |
| December 31, 2023 | 990 | $37,726,467 | $24,856,709 | $12,869,758 | $125,553,981 | $4,301,968 | $121,252,013 |
Financial details: 990 for the year ended December 31, 2024
Revenue
- Contributions, gifts and grants
- $18,634,211
- of which government grants
- $13,773,853
- Program service revenue
- $0
- Investment income
- $687,795
- Net gain from sales of assets
- -$8,333
- Other revenue
- $630,691
Expenses
- Grants and similar amounts paid
- $170,000
- Compensation of officers, directors and key employees
- $685,846
- Other salaries and wages
- $9,264,990
- Salaries, compensation and benefits (total)
- $12,804,246
- Professional fundraising fees
- $0
- Legal fees
- $168,357
- Accounting fees
- $68,500
- Occupancy
- $867,148
- Travel
- $57,980
- Depreciation
- $8,416,640
- Program services (functional)
- $23,796,275
- Management and general (functional)
- $4,657,527
Balance sheet and other
- Total assets, start of year
- $125,553,981
- Total assets, end of year
- $133,938,928
- Total liabilities, end of year
- $11,192,289
- Net assets, end of year
- $122,746,639
- Land, buildings and equipment
- $92,245,620
- Publicly traded securities
- $15,241,225
- Net assets without donor restrictions
- $106,207,663
- Net assets with donor restrictions
- $16,538,976
- Gross receipts
- $19,961,030
- Employees
- 85
- Volunteers
- 17
- Year formed
- 1999
- State of legal domicile
- NY
From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.
Officers, directors and key employees
As listed on the 990 for the year ended December 31, 2024, highest compensation first.
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| DR JEFFREY KIEFT | EXECUTIVE DIRECTOR Officer | 40 | $581,635 | $104,211 |
| DR ALEX DE MARCO | SEMC DIRECTOR Highest-paid employee | 40 | $372,535 | $104,211 |
| MR ARJUN KOSHAL | MANAGING DIRECTOR Highest-paid employee | 40 | $320,368 | $85,604 |
| MS DEBBIE TRIFILIO | DIRECTOR OF FINANCE AND OPERATIONS Highest-paid employee | 40 | $259,823 | $64,200 |
| DR KEVIN BATTAILE | NYS BEAMLINE DIRECTOR/LEAD SCIENTIST Highest-paid employee | 40 | $260,599 | $41,771 |
| DR MICHAEL GOGER | SENIOR SCIENTIST & NMR MANAGER Highest-paid employee | 40 | $218,979 | $22,742 |
| DR KEVIN GARDNER | CHAIRMAN Trustee or director, Officer | 4 | $0 | $0 |
| DR FREDERICK MAXFIELD | SECRETARY Trustee or director, Officer | 0.1 | $0 | $0 |
| DR TIMOTHY P O'CONNOR | TREASURER Trustee or director, Officer | 0.2 | $0 | $0 |
| DR ANEEL AGGARWAL | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR STEVEN C ALMO | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR DAVID COWBURN | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR SETH DARST | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR DAVID HIRSH | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR NINA GRAY | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
8 more people on this return
| Name | Title | Hours / week | Compensation |
|---|---|---|---|
| DR PILAR COSSIO | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR RAJENDRA K AGRAWAL | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR CHRISTOPHER LIMA | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR TONY M LISS | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR STEPHEN LONG | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR ANN MCDERMOTT | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR CRINA NIMIGEAN | BOARD MEMBER Trustee or director | 0.1 | $0 |
| DR MING-MING ZHOU | BOARD MEMBER Trustee or director | 0.1 | $0 |
990 for the year ended December 31, 2023: 26 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| DR JEFFREY KIEFT | EXECUTIVE DIRECTOR (FROM 5/1/23) Officer | 37.5 | $509,675 | $47,422 |
| MR ARJUN KOSHAL | MANAGING DIRECTOR Highest-paid employee | 37.5 | $298,811 | $80,211 |
| DR KEVIN BATTAILE | NYX BEAMLINE DIRECTOR Highest-paid employee | 37.5 | $244,149 | $38,736 |
| DR ALEX DE MARCO | SEMC DIRECTOR (FROM 5/1/23) Highest-paid employee | 37.5 | $236,521 | $41,922 |
| DR WILLA APPEL | EXECUTIVE DIRECTOR (TO 4/30/23) Officer | 37.5 | $199,975 | $65,121 |
| MS DEBBIE TRIFILIO | DIRECTOR OF FINANCE Highest-paid employee | 37.5 | $187,780 | $48,082 |
| DR MICHAEL GOGER | SENIOR SCIENTIST AND NMR MANAGER Highest-paid employee | 37.5 | $210,557 | $21,267 |
| DR DAVID HIRSH | CHAIRMAN Trustee or director, Officer | 4 | $0 | $0 |
| DR FREDERICK MAXFIELD | SECRETARY Trustee or director, Officer | 0.1 | $0 | $0 |
| DR TIMOTHY P O'CONNOR | TREASURER Trustee or director, Officer | 0.2 | $0 | $0 |
| DR STEVEN C ALMO | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR DAVID COWBURN | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR TONY M LISS | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR KEVIN H GARDNER | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR ANN MCDERMOTT | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR CHRISTOPHER LIMA | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR NINA GRAY | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR MING-MING ZHOU | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR CRINA NIMIGEAN | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR LESLIE GREENGARD | BOARD MEMBER (TO 3/13/23) Trustee or director | 0.1 | $0 | $0 |
| DR SETH DARST | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR DAVID LEMASTER | BOARD MEMBER (TO 7/10/23) Trustee or director | 0.1 | $0 | $0 |
| DR STEPHEN LONG | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR ANEEL AGGARWAL | BOARD MEMBER Trustee or director | 0.1 | $0 | $0 |
| DR PILAR COSSIO | BOARD MEMBER (FROM 3/13/23) Trustee or director | 0.1 | $0 | $0 |
| DR RAJENDRA K AGRAWAL | BOARD MEMBER (FROM 7/10/23) Trustee or director | 0.1 | $0 | $0 |
Address and contacts
- Address (IRS master file)
- 89 CONVENT AVE 133RD ST, NEW YORK, NY 10027-0000
- Principal officer (990 for 2024)
- DR JEFFREY KIEFT, 89 CONVENT AVE 133RD ST, NEW YORK, NY 10027
- Signed the 990
- DR JEFFREY KIEFT, EXECUTIVE DIRECTOR
- Phone
- (212) 939-0660
- Website
- WWW.NYSBC.ORG
- Return prepared by
- BONADIO & CO LLP
Mission
THE NYSBC MISSION IS TO PROVIDE ADVANCED RESEARCH RESOURCES TO THE FACULTY OF ITS PARTICIPATING MEMBER INSTITUTIONS AND RESEARCHERS FROM THE NATIONAL COMMUNITY IN THREE KEY AREAS OF STRUCTURAL BIOLOGY: NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; CRYOELECTRON MICROSCOPY; AND X-RAY CRYSTALLOGRAPHY.
Program accomplishments
- RESEARCH CONDUCTED AT THE SIMONS ELECTRON MICROSCOPY CENTER (SEMC) IS AIMED AT DETERMINING THE STRUCTURE OF MACROMOLECULES TO HELP UNDERSTAND THEIR FUNCTION. AS OF DECEMBER 31, 2024, THE FACILITY HAD 15 TRANSMISSION ELECTRON MICROSCOPES, 3 DUAL-BEAM FOCUSED ION BEAM SCANNING ELECTRON MICROSCOPES, AS WELL AS ANCILLARY EQUIPMENT FOR CRYOEM SAMPLE PREPARATION. SEMC SERVES USERS FROM NYSBC'S NINE MEMBER INSTITUTIONS AS WELL AS USERS FROM THE NATIONAL COMMUNITY THROUGH NIH-FUNDED CENTERS (NATIONAL CENTER FOR CRYOEM ACCESS AND TRAINING AND NATIONAL CENTER FOR IN-SITU TOMOGRAPHIC ULTRAMICROSCOPY). SEMC DEVELOPS OPEN-SOURCE TECHNOLOGIES TO ACCELERATE CRYOEM WORKFLOWS FROM SAMPLE PREPARATION TO STRUCTURE DETERMINATION THROUGH ITS SIMONS FOUNDATION INITIATIVES (SIMONS RESOURCE FOR AUTOMATED MOLECULAR MICROSCOPY AND SIMONS MACHINE LEARNING CENTER). SEMC ALSO PROVIDES EXTENSIVE TRAINING TO MEMBERS OF THE COMMUNITY THROUGH WORKSHOPS, COURSES, AND OTHER TRAINING SESSIONS. IN SEVERAL PROJECTS, SEMC STAFF HAS BEEN INVOLVED EXTENSIVELY AS COLLABORATORS DEVELOPING NEW MACHINE LEARNING ALGORITHMS AND SOFTWARE FOR AUTOMATING CRYOEM, AND CONTRIBUTING TO SOLVING THE STRUCTURES OF: CRISPR-CAS COMPLEXES, ION CHANNELS, GPCRS, AND MANY DRUG TARGETS, E.G., AGAINST DISEASES LIKE COVID-19. OVER 200 SCIENTIFIC ARTICLES ACKNOWLEDGED SEMC SUPPORT IN 2024.Expenses $15,668,535
- NYSBC PROVIDES ACCESS TO HIGH-FIELD NUCLEAR MAGNETIC RESONANCE (NMR) SPECTROSCOPY TO FACULTY FROM ITS NINE MEMBER INSTITUTIONS. THE NMR FACILITY INSTRUMENTATION INCLUDES NINE NMR SPECTROMETERS THAT GENERALLY OPERATE 24 HRS/DAY, 7 DAYS/WEEK. IN 2024, EACH SPECTROMETER WAS AVAILABLE, ON AVERAGE, 345 DAYS. THESE RESOURCES ALLOW RESEARCHERS TO DETERMINE THE STRUCTURE OF PROTEINS IN SOLUTION AND IN SOLID STATE ATOMIC RESOLUTION, DATA THAT PROVIDES INSIGHT INTO THE FUNCTIONAL PROPERTIES OF THE PROTEINS. IN 2024, GROUP MEMBERS FROM THE LABORATORIES OF 17 AFFILIATED PRINCIPAL INVESTIGATORS MADE USE OF THESE INSTRUMENTS. DATA COLLECTED WITH THESE INSTRUMENTS PRODUCED 18 PUBLICATIONS IN EMINENT SCIENTIFIC JOURNALS. THE CENTER OPERATES THE CENTER ON MOLECULAR DYNAMICS BY COMD/NMR, A BIOMEDICAL TECHNOLOGY RESEARCH RESOURCE SUPPORTED BY U.S. NATIONAL INSTITUTES OF HEALTH GRANTS RM1 GM145397 AND LOCATED AT NYSBC. THE MISSION OF COMD-NMR IS TO MAKE AVAILABLE TO THE BIOLOGICAL RESEARCH COMMUNITY ADVANCED NMR SPECTROSCOPIC AND COMPUTATIONAL METHODS FOR CHARACTERIZING PROTEIN AND NUCLEIC ACID CONFORMATIONAL DYNAMICS IN BIOLOGICAL PROCESSES.Expenses $3,119,947 · grants $120,000
- NYSBC HAS MAINTAINED X-RAY CRYSTALLOGRAPHY RESOURCES AT BROOKHAVEN NATIONAL LABORATORY (BNL) SINCE 2003. NYSBC HAS DEVELOPED AND OPERATES BEAMLINE 19ID-NYX AT THE NATIONAL SYNCHROTRON LIGHT SOURCE II (NSLS-II). NYX PROVIDES THE NYSBC MEMBER INSTITUTIONS AND ASSOCIATED INVESTIGATORS WITH ACCESS TO SYNCHROTRON RADIATION AND INSTRUMENTATION NECESSARY FOR COLLECTING CRYSTALLOGRAPHIC DATA ON BIOLOGICAL MACROMOLECULES. NYX HAS PERFORMED TECHNICAL AND SCIENTIFIC COMMISSIONING AND STARTED USER OPERATIONS IN THE SPRING OF 2019. THE PRIMARY ACCOMPLISHMENTS OF THE BEAMLINE PROGRAM FOR 2024 WERE UPGRADES TO AUTOMATION AND SOFTWARE AND SUPPORTING USER EXPERIMENTS.Expenses $1,433,633
- SPECIAL PROJECTS GROUP: THE SPECIAL PROJECTS GROUP AT NYSBC IS A TEAM OF EXPERT SCIENTISTS THAT PERFORMS FEE-FOR-SERVICE PROTEIN STRUCTURE DETERMINATION AND PROTEIN PRODUCTION SERVICES FOR EXTERNAL CLIENTS. IN ADDITION, THEY ALSO RECEIVE FUNDING THROUGH COLLABORATIVE RESEARCH PROJECTS WITH ACADEMIC AND GOVERNMENT LABORATORIES. THEY ENTERED THE SECOND YEAR OF A FIVE-YEAR NIAID CONTRACT USING STRUCTURAL BIOLOGY TO INVESTIGATE THE ETIOLOGIC AGENT FOR LYME DISEASE, BORRELIELLA BURGDORFERI, TO DESIGN A VACCINE OR DISCOVER ANTIBODY THERAPEUTICS AGAINST LYME DISEASE. THEY ALSO CONTINUED TO PARTICIPATE IN STRUCTURAL BIOLOGY RESEARCH PROJECTS ENTERING THE SECOND YEAR OF A FIVE-YEAR NIAID GRANT WITH COLLABORATORS AT RUTGERS UNIVERSITY INVESTIGATING RICIN AND SHIGA TOXINS TO RATIONALLY DESIGN BETTER INHIBITORS AGAINST THESE TWO TOXINS. IN ADDITION, THE TEAM HAS INITIATED NIH-FUNDED WORK IN A COLLABORATIVE EFFORT WITH RESEARCHERS AT VIRGINIA COMMONWEALTH UNIVERSITY THAT INVOLVES STRUCTURAL CHARACTERIZATION OF A CONSERVED STREPTOCOCCAL MEMBRANE PROTEIN THAT AFFECTS MANGANESE UTILIZATION.RNA LAB: THE RNA RESEARCH CONDUCTED AT NYSBC FOCUSES ON UNDERSTANDING HOW THE 3-DIMENSIONAL STRUCTURES OF RNA FORM AND HOW THIS STRUCTURE, CONFORMATIONAL DYNAMICS, AND INTERACTIONS WITH OTHER MOLECULES ENABLE DIVERSE BIOLOGICAL FUNCTION. THIS NIH-FUNDED EFFORT IS PRIMARILY CENTERED ON UNDERSTANDING RNAS OF VIRAL ORIGIN, WITH PARTICULAR INTEREST IN HOW THESE VIRAL RNAS INTERACT WITH THE CELLULAR MACHINERY AND MANIPULATE THAT MACHINERY. THE RNA GROUP CONSISTS OF RESEARCHERS AT SEVERAL LEVELS OF TRAINING AND EXPERIENCE, WHO EMPLOY AND INTEGRATE BIOCHEMICAL, BIOPHYSICAL, STRUCTURAL, AND BIOINFORMATIC APPROACHES. THIS RESEARCH PROGRAM IS WORLD RESPECTED AND FREQUENTLY PUBLISHES IN THE HIGHEST IMPACT JOURNALS.Expenses $3,574,160 · grants $50,000
What it must file and when
IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.
| Tax year | Year ended | Due | IRS public records |
|---|---|---|---|
| 2025 | December 31, 2025 | May 15, 2026 | Not on file |
| 2024 | December 31, 2024 | May 15, 2025 | 990 on file |
| 2023 | December 31, 2023 | May 15, 2024 | 990 on file |
IRS record
- EIN
- 13-4043587
- Tax-exempt status
- 501(c)(3): Charitable, religious, educational or scientific organization
- Foundation status
- Publicly supported organization (170(b)(1)(A)(vi))
- Donations deductible (Pub 78)
- Public charity, 50% deduction limit
- Exempt since
- 1999
- Accounting year ends
- December
- Files
- Form 990 or 990-EZ
- Category (NTEE)
- Science and technology (U500)
- Assets (IRS master file)
- $133,938,928
- Income (IRS master file)
- $19,961,030
Filing history
| Form | Year ended | Revenue | Expenses | Assets | Return |
|---|---|---|---|---|---|
| 990 | December 2024 | $19,952,697 | $28,453,802 | $133,938,928 | XML |
| 990 | December 2023 | $37,726,467 | $24,856,709 | $125,553,981 | XML |
| 990 | December 2022 | $28,684,129 | $23,931,083 | $110,945,662 | IRS |
| 990 | December 2021 | – | – | – | IRS |
| 990 | December 2020 | – | – | – | IRS |
| 990 | December 2018 | – | – | – | IRS |
| 990 | December 2017 | – | – | – | IRS |
990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 13-4043587).
Questions about NEW YORK STRUCTURAL BIOLOGY CENTER INC
- What is the EIN of NEW YORK STRUCTURAL BIOLOGY CENTER INC?
- The employer identification number (EIN) of NEW YORK STRUCTURAL BIOLOGY CENTER INC is 13-4043587.
- Is NEW YORK STRUCTURAL BIOLOGY CENTER INC tax-exempt?
- Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 1999.
- Are donations to NEW YORK STRUCTURAL BIOLOGY CENTER INC tax-deductible?
- Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
- Which annual return does NEW YORK STRUCTURAL BIOLOGY CENTER INC file?
- Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
- When is the next return of NEW YORK STRUCTURAL BIOLOGY CENTER INC due?
- The return for tax year 2025 (the year ending December 31, 2025) is due May 15, 2026. Form 8868 extends it by six months; the 990-N cannot be extended.
- When did NEW YORK STRUCTURAL BIOLOGY CENTER INC last file with the IRS?
- The latest return in the IRS public files is the 990 for the year ended December 2024.
- Who is the principal officer of NEW YORK STRUCTURAL BIOLOGY CENTER INC?
- The 990 for the year ended December 31, 2024 names DR JEFFREY KIEFT.
- Who are the officers and directors of NEW YORK STRUCTURAL BIOLOGY CENTER INC?
- The 990 for the year ended December 31, 2024 lists 23 people; 6 received compensation from the organization, the highest $581,635 (DR JEFFREY KIEFT, EXECUTIVE DIRECTOR).
- How much revenue does NEW YORK STRUCTURAL BIOLOGY CENTER INC have?
- On its 990 for the year ended December 31, 2024 it reported revenue of $19,952,697, expenses of $28,453,802 and total assets of $133,938,928 at year end.
Other nonprofits in NEW YORK
- AMERICAN SOCIETY OF MECHANICAL ENGINEERS EIN 13-1623899 · last filed 990 for 2025
- RENAISSANCE PHILANTHROPY FUND EIN 99-1953380 · last filed 990 for 2025
- ASSOCIATION FOR COMPUTING MACHINERY INC EIN 13-1921358 · last filed 990 for 2025
- SCRATCH FOUNDATION EIN 46-2612143 · last filed 990 for 2024
- PROJECT LIBERTY INSTITUTE EIN 87-3213298 · last filed 990 for 2025
- EMPIRE AI CONSORTIUM EIN 99-4209088 · last filed 990 for 2025
- EXPLORERS CLUB EIN 13-1866795 · last filed 990 for 2025
- WORLD SCIENCE FOUNDATION EIN 43-2095418 · last filed 990 for 2025
All nonprofits in NEW YORK · New York · Science and technology