Nonprofit · EIN 04-3460220
THE PROGERIA RESEARCH FOUNDATION INC
Also known as PREMATURE AGING IN CHILD-PROG RES F
Tax-exempt · PEABODY, MA 01961
Financials
| Year ended | Form | Revenue | Expenses | Net income | Total assets | Liabilities | Net assets |
|---|---|---|---|---|---|---|---|
| December 31, 2025 | 990 | $4,458,016 | $4,163,643 | $294,373 | $49,979,002 | $526,805 | $49,452,197 |
| December 31, 2024 | 990 | $3,650,308 | $5,902,368 | -$2,252,060 | $48,028,500 | $627,829 | $47,400,671 |
| December 31, 2023 | 990 | $2,231,500 | $3,929,965 | -$1,698,465 | $48,844,685 | $593,519 | $48,251,166 |
Financial details: 990 for the year ended December 31, 2025
Revenue
- Contributions, gifts and grants
- $2,020,617
- of which government grants
- $98,625
- Program service revenue
- $0
- Investment income
- $2,433,984
- Net gain from sales of assets
- $559,351
- Net income from fundraising events
- $3,415
- Other revenue
- $3,415
Expenses
- Grants and similar amounts paid
- $0
- Compensation of officers, directors and key employees
- $608,187
- Other salaries and wages
- $556,167
- Salaries, compensation and benefits (total)
- $1,300,190
- Professional fundraising fees
- $0
- Legal fees
- $280,397
- Accounting fees
- $64,008
- Occupancy
- $55,180
- Travel
- $9,240
- Depreciation
- $19,319
- Program services (functional)
- $3,024,716
- Management and general (functional)
- $930,856
- Fundraising (functional)
- $208,071
Balance sheet and other
- Total assets, start of year
- $48,028,500
- Total assets, end of year
- $49,979,002
- Total liabilities, end of year
- $526,805
- Net assets, end of year
- $49,452,197
- Land, buildings and equipment
- $20,447
- Publicly traded securities
- $41,294,699
- Net assets without donor restrictions
- $49,332,586
- Net assets with donor restrictions
- $119,611
- Gross receipts
- $7,933,487
- Employees
- 15
- Volunteers
- 60
- Year formed
- 1999
- State of legal domicile
- MA
From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.
Officers, directors and key employees
As listed on the 990 for the year ended December 31, 2025, highest compensation first.
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| BARBARA NATKE | CHIEF BUSINESS OFFICER Key employee | 40 | $319,523 | $0 |
| AUDREY GORDON | PRESIDENT & EXECUTIVE DIRECTOR Officer | 40 | $256,385 | $32,279 |
| MICHELLE FINO | DIRECTOR OF DEVELOPMENT Highest-paid employee | 40 | $114,478 | $6,031 |
| GINA INCROVATO | DIRECTOR OF OPERATIONS Highest-paid employee | 40 | $113,512 | $0 |
| SCOTT BERNS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| PAULA KELLY | TREASURER/DIRECTOR Trustee or director, Officer | 1 | $0 | $0 |
| KAREN BALLACK | DIRECTOR Trustee or director | 1 | $0 | $0 |
| SANDRA BRESNICK | DIRECTOR Trustee or director | 1 | $0 | $0 |
| KIM PARATORE | CLERK/DIRECTOR Trustee or director, Officer | 1 | $0 | $0 |
| JOHN MAROZZI | DIRECTOR Trustee or director | 1 | $0 | $0 |
| LARRY MILLS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| LIZA MORRIS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| MATTHEW WINTERS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| MARK KIERAN | DIRECTOR Trustee or director | 1 | $0 | $0 |
| ALAN BROGDON | DIRECTOR Trustee or director | 1 | $0 | $0 |
990 for the year ended December 31, 2024: 15 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| BARBARA NATKE | CHIEF BUSINESS OFFICER Key employee | 40 | $307,689 | $755 |
| AUDREY GORDON | PRESIDENT Officer | 40 | $230,000 | $20,427 |
| JASON CHRISTIANSEN | GENERAL COUNSEL Highest-paid employee | 40 | $173,656 | $0 |
| MICHELLE FINO | DIRECTOR OF DEVELOPMENT Highest-paid employee | 40 | $100,253 | $0 |
| SCOTT BERNS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| PAULA KELLY | TREASURER/DIRECTOR Trustee or director, Officer | 1 | $0 | $0 |
| KAREN BALLACK | DIRECTOR Trustee or director | 1 | $0 | $0 |
| SANDRA BRESNICK | DIRECTOR Trustee or director | 1 | $0 | $0 |
| KIM PARATORE | CLERK/DIRECTOR Trustee or director, Officer | 1 | $0 | $0 |
| JOHN MAROZZI | DIRECTOR Trustee or director | 1 | $0 | $0 |
| LARRY MILLS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| LIZA MORRIS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| MATTHEW WINTERS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| MARK KIERAN | DIRECTOR Trustee or director | 1 | $0 | $0 |
| ALAN BROGDON | DIRECTOR Trustee or director | 1 | $0 | $0 |
990 for the year ended December 31, 2023: 12 people
| Name | Title | Hours / week | Compensation | Other / benefits |
|---|---|---|---|---|
| AUDREY GORDON | PRESIDENT Officer | 40 | $235,000 | $20,427 |
| BARBARA NATKE | CHIEF BUSINESS OFFICER Highest-paid employee | 40 | $143,475 | $755 |
| SCOTT BERNS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| PAULA KELLY | TREASURER/DIRECTOR Trustee or director, Officer | 1 | $0 | $0 |
| KAREN BALLACK | DIRECTOR Trustee or director | 1 | $0 | $0 |
| SANDRA BRESNICK | DIRECTOR Trustee or director | 1 | $0 | $0 |
| KIM PARATORE | CLERK/DIRECTOR Trustee or director, Officer | 1 | $0 | $0 |
| JOHN MAROZZI | DIRECTOR Trustee or director | 1 | $0 | $0 |
| LARRY MILLS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| LIZA MORRIS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| MATTHEW WINTERS | DIRECTOR Trustee or director | 1 | $0 | $0 |
| MARK KIERAN | DIRECTOR Trustee or director | 1 | $0 | $0 |
Address and contacts
- Address (IRS master file)
- PO BOX 3453, PEABODY, MA 01961-3453
- In care of
- % AUDREY S GORDON
- Principal officer (990 for 2025)
- AUDREY GORDON ESQ, 200 LAKE STREET, PEABODY, MA 01960
- Signed the 990
- AUDREY GORDON ESQ, PRESIDENT, EXECUTIVE DIRECTOR
- Phone
- (978) 535-2594
- Website
- WWW.PROGERIARESEARCH.ORG
- Return prepared by
- CITRIN COOPERMAN ADVISORS LLC
Mission
DISCOVER TREATMENTS & CURE FOR PROGERIA & ITS AGING RELATED DISORDERS, INCLUDING HEART DISEASE.
Program accomplishments
- PROGERIA DRUG TRIAL: THE PROGERIA RESEARCH FOUNDATION AND BOSTON CHILDREN'S HOSPITAL CONTINUE THEIR PARTNERSHIP FOR CONDUCTING CLINICAL DRUG TRIALS FOR CHILDREN WITH PROGERIA. THE CLINICAL TRIAL TEAM: A TEAM OF PROFESSIONALS AT BOSTON CHILDREN'S HOSPITAL AND BRIGHAM & WOMEN'S HOSPITAL WORKING WITH CHILDREN WITH PROGERIA FROM AROUND THE GLOBE.Expenses $927,130
- FUTURE TRIAL EFFORTS: PRF ENGAGES MEMBERS IN THE SCIENTIFIC COMMUNITY WITH EXPERTISE IN VARIOUS DRUGS AND/OR GENETIC THERAPIES FOR THE TREATMENT AND POTENTIAL CURE FOR PROGERIA. THE INVESTIGATION AND COLLABORATIVE EVALUATION OF DRUG THERAPIES IS PURSUED TO IDENTIFY DRUG CANDIDATES/GENETIC THERAPIES THAT CAN LEAD TO FUTURE CLINICAL TRIALS.Expenses $574,601
- DIAGNOSTIC TESTING: PRF DEVELOPED A DIAGNOSTIC TEST FOR PROGERIA IN THE WAKE OF THE 2003 GENE DISCOVERY SO THOSE WITH PROGERIA, THEIR FAMILIES AND MEDICAL CARETAKERS CAN FOR THE FIRST TIME BE GIVEN A DEFINITIVE SCIENTIFIC DIAGNOSIS. THIS CAN TRANSLATE INTO EARLIER DIAGNOSIS, FEWER MISDIAGNOSES AND EARLY MEDICAL INTERVENTION TO ENSURE A BETTER QUALITY OF LIFE FOR THOSE WITH PROGERIA.(SEE SCHEDULE O FOR CONTINUATION)MEDICAL & RESEARCH DATABASE: THE DATABASE IS A COLLECTION OF MEDICAL RECORDS OF PROGERIA PATIENTS FROM ALL OVER THE WORLD. THE DATA IS RIGOROUSLY ANALYZED TO DETERMINE THE BEST COURSE OF TREATMENTS TO IMPROVE THE PATIENTS' QUALITY OF LIFE. THIS INFORMATION IS INVALUABLE FOR THE ATTENDING PHYSICIAN TO GUIDE THE FAMILY THROUGH THE BEST COURSE OF ACTION. DATABASE MATERIAL WAS USED TO CREATE PRF'S COMPREHENSIVE HEALTHCARE RECOMMENDATIONS HANDBOOK ON PROGERIA AIMED AT OPTIMIZING QUALITY OF LIFE. THE DATABASE WAS ALSO CRITICAL IN DETERMINING THE PRIMARY CLINICAL OUTCOME PARAMETER FOR PAST PROGERIA CLINICAL DRUG TRIALS.PRF TRANSLATION PROGRAM: IN TOUCH WITH THE WORLD. WITH A PROMINENT GLOBAL OUTREACH, PRF ELIMINATES BARRIERS OF COMMUNICATION FOR PATIENTS AND THEIR FAMILIES AROUND THE WORLD. THIS INITIATIVE HAS SUCCEEDED IN TRANSLATING PRF PROGRAM AND MEDICAL CARE MATERIALS INTO OVER 3 DOZEN DIFFERENT LANGUAGES.THE PROGERIA HANDBOOK: A GUIDE FOR FAMILIES AND HEALTH CARE PROVIDERS OF CHILDREN AND YOUNG ADULTS WITH PROGERIA THAT INCLUDES DAILY CARE RECOMMENDATIONS AND EXTENSIVE TREATMENT GUIDELINES. IT IS PUBLISHED IN ENGLISH AND SEVERAL OTHER LANGUAGES TO ALLOW ITS USE THROUGHOUT THE WORLD.INTERNATIONAL PROGERIA REGISTRY: CONSISTS OF CENTRALIZED CONTACT AND OTHER INFORMATION ON CHILDREN AND FAMILIES LIVING WITH PROGERIA. THE REGISTRY PROVIDES DATA ON PATIENT DEMOGRAPHICS AND ASSURES RAPID DISTRIBUTION OF ANY NEW INFORMATION THAT MAY BENEFIT THOSE WITH PROGERIA.SCIENTIFIC CONFERENCES; PRF ORGANIZES MEETINGS THAT BRING TOGETHER SCIENTISTS AND CLINICIANS FROM ALL OVER THE WORLD TO SHARE THEIR EXPERTISE AND CUTTING EDGE SCIENTIFIC DATA, AND FOSTER COLLABORATION IN THE FIGHT AGAINST PROGERIA AND OTHER AGING RELATED CONDITIONS.CLINICAL TRIALS: IN 2025, 7 CHILDREN AND YOUNG ADULTS CAME TO BOSTON TO UNDERGO TESTING AND OBTAIN LONAFARNIB FOR THE PROLON 3 (LONAFARNIB EXTENSION) TRIAL, WHICH ALLOWS CHILDREN AND YOUNG ADULTS WHO ARE UNABLE TO OBTAIN LONAFARNIB IN THEIR HOME COUNTRY TO RECEIVE THIS LIFE EXTENDING TREATMENT THROUGH THIS TRIAL, WHILE ALSO GATHERING IMPORTANT DISEASE-RELATED DATA. IN 2025, THE TEAM CONTINUES TO GATHER DATA FROM THE ONGOING CLINICAL DRUG TRIAL. IN ADDITION, PRF COLLABORATED WITH PRG SCIENCE & TECHNOLOGY IN A TRIAL INVOLVING THE DRUG PROGERININ. TEN CHILDREN AND YOUNG ADULTS CAME TO BOSTON THREE TIMES IN 2025 TO PARTICIPATE IN THE TRIAL. ONE OF THE 10 PARTICIPANTS ONE ALSO PARTICIPATED IN THE PROLON 3 TRIAL SIMULTANEOUSLY DURING ONE OF THE VISITS.Expenses $1,522,985
What it must file and when
IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.
| Tax year | Year ended | Due | IRS public records |
|---|---|---|---|
| 2025 | December 31, 2025 | May 15, 2026 | 990 on file |
| 2024 | December 31, 2024 | May 15, 2025 | 990 on file |
| 2023 | December 31, 2023 | May 15, 2024 | 990 on file |
IRS record
- EIN
- 04-3460220
- Tax-exempt status
- 501(c)(3): Charitable, religious, educational or scientific organization
- Foundation status
- Publicly supported organization (170(b)(1)(A)(vi))
- Donations deductible (Pub 78)
- Public charity, 50% deduction limit
- Exempt since
- 1999
- Accounting year ends
- December
- Files
- Form 990 or 990-EZ
- Category (NTEE)
- Medical research (H122)
- Assets (IRS master file)
- $49,979,002
- Income (IRS master file)
- $7,933,487
Filing history
| Form | Year ended | Revenue | Expenses | Assets | Return |
|---|---|---|---|---|---|
| 990 | December 2025 | $4,458,016 | $4,163,643 | $49,979,002 | XML |
| 990 | December 2024 | $3,650,308 | $5,902,368 | $48,028,500 | XML |
| 990 | December 2023 | $2,231,500 | $3,929,965 | $48,844,685 | XML |
| 990 | December 2022 | $1,793,850 | $3,126,766 | $47,596,733 | IRS |
| 990 | December 2021 | – | – | – | IRS |
| 990 | December 2020 | – | – | – | IRS |
| 990 | December 2018 | – | – | – | IRS |
990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 04-3460220).
Questions about THE PROGERIA RESEARCH FOUNDATION INC
- What is the EIN of THE PROGERIA RESEARCH FOUNDATION INC?
- The employer identification number (EIN) of THE PROGERIA RESEARCH FOUNDATION INC is 04-3460220.
- Is THE PROGERIA RESEARCH FOUNDATION INC tax-exempt?
- Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 1999.
- Are donations to THE PROGERIA RESEARCH FOUNDATION INC tax-deductible?
- Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
- Which annual return does THE PROGERIA RESEARCH FOUNDATION INC file?
- Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
- When is the next return of THE PROGERIA RESEARCH FOUNDATION INC due?
- The return for tax year 2026 (the year ending December 31, 2026) is due May 17, 2027. Form 8868 extends it by six months; the 990-N cannot be extended.
- When did THE PROGERIA RESEARCH FOUNDATION INC last file with the IRS?
- The latest return in the IRS public files is the 990 for the year ended December 2025.
- Who is the principal officer of THE PROGERIA RESEARCH FOUNDATION INC?
- The 990 for the year ended December 31, 2025 names AUDREY GORDON ESQ.
- Who are the officers and directors of THE PROGERIA RESEARCH FOUNDATION INC?
- The 990 for the year ended December 31, 2025 lists 15 people; 4 received compensation from the organization, the highest $319,523 (BARBARA NATKE, CHIEF BUSINESS OFFICER).
- How much revenue does THE PROGERIA RESEARCH FOUNDATION INC have?
- On its 990 for the year ended December 31, 2025 it reported revenue of $4,458,016, expenses of $4,163,643 and total assets of $49,979,002 at year end.
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