2026-07-24T07:38:54-05:00 2025-09-30 042713795 MEYERS BROTHERS KALICKA PC 330 WHITNEY AVE SUITE 800 HOLYOKE MA 01040 990 2024-10-01 571183126 PIONEER VALLEY LIFE SCIENCES INSTITUTE OF BAYSTATE MEDICAL & UMASS AMHERSTINC PION 4137947833 3601 MAIN STREET SPRINGFIELD MA 01001 LAURIE MARTIN CFO & TREASURER 4137947833 2026-07-21 1 1 RUDY M D'AGOSTINO P00962620 4135368510 2026-07-21 2024 2025-03-06 01:10:19Z LAURIE MARTIN 280 CHESTNUT STREET SPRINGFIELD MA 01199 0 0 X PVLSI.ORG X 2004 MA IMPROVE HUMAN HEALTH BY DEVELOPING NEW APPROACHES FOR THE DIAGNOSIS & TREATMENT OF DISEASE. 10 10 0 13 0 0 82298 0 0 0 0 0 0 0 82298 0 0 0 0 0 0 0 0 0 0 226896 234063 226896 234063 -144598 -234063 756115 590935 335521 404404 420594 186531 X TO IMPROVE HUMAN HEALTH BY DEVELOPING CREATIVE NEW APPROACHES FOR THE DIAGNOSIS AND TREATMENT OF DISEASE. 0 0 71598 BREAST REGISTRY DESCRIPTION: ANALYSIS-READY DATASETS WITH PATIENT CHARACTERISTICS TOGETHER WITH TREATMENTS AND OUTCOMES ARE ESSENTIAL TO MONITOR SUCCESS IN DIAGNOSIS AND CLINICAL MANAGEMENT OF DISEASE AND IDENTIFY GAPS THAT EXIST. WE HAVE CREATED A PROSPECTIVE REGISTRY FOCUSED ON BREAST CANCER. THIS RESOURCE INCLUDES A DETAILED SURVEY OF LIFESTYLE, HEALTH HISTORY, DIAGNOSTIC, TREATMENT INFORMATION, AND OUTCOMES. TISSUE SPECIMENS ARE AVAILABLE FOR ALL THE PARTICIPANTS. ACCOMPLISHMENTS: PRESENT ENROLLMENT IS 1,565 PARTICIPANTS. 71598 TISSUE AND CELL BIOREPOSITORY DESCRIPTION: NORMAL AND CANCER CELLS FROM A DIVERSE COHORT OF PATIENTS IS NEEDED TO IDENTIFY CELLULAR MECHANISMS RESPONSIBLE FOR THE WIDE VARIATION IN RESPONSES TO THERAPIES AMONG INDIVIDUALS. THE EFFORT HAS EMPHASIZED COLLECTIONS OF NORMAL BREAST EPITHELIAL CELLS FROM PARTICIPANTS AND DEVELOPMENT OF METHODS TO CREATE STABLE CELL LINES REPRESENTING THE GENETIC AND EPIGENETIC DIVERSITY IN THE POPULATION OF WOMEN. TUMOR TISSUES ARE ALSO AVAILABLE FOR CREATING CELL AND TRANSPLANT MODELS OF BREAST CANCERS.ACCOMPLISHMENTS: BREAST TISSUES HAVE BEEN COLLECTED FOR FIXATION AND FROZEN SAMPLE FROM 670 WOMEN. PRIMARY CULTURES OF BREAST EPITHELIAL CELLS HAVE BEEN DISSOCIATED AND FROZEN FOR APPROXIMATELY 425 WOMEN. WE HAVE CREATED AND CHARACTERIZED IMMORTALIZED CELL LINES FROM 16 PARTICIPANTS WHICH ARE NOW AVAILABLE TO ACADEMIC RESEARCHERS. WHEN GROWN IN 3D MATRIX, THE CELL LINES FORM DUCTLIKE STRUCTURES TO MODEL NORMAL BREAST AND FORM TUMORS WHEN EXPOSED TO CHEMICALS OR WHEN ONCOGENES ARE INTRODUCED. THE OVARIAN REPOSITORY CONTAINS OVARIAN TISSUES AND MATCHING BLOODS FROM 160 DONORS. 71598 HISTOLOGICAL SERVICES (HISTOSPRING): THE FACILITY MAINTAINS THE EQUIPMENT AND PERSONNEL TO PROVIDE HISTOLOGICAL SERVICES TO ASSIST INVESTIGATORS WITH ANALYSIS OF TISSUE SPECIMENS AS WELL AS SUPPORTING IRB SUBMISSIONS AND TISSUE PROCUREMENT. ACCOMPLISHMENTS: PROVIDE HISTOLOGICAL SERVICES TO RESEARCHERS AT UMASS AMHERST, UMASS MEDICAL SCHOOL, BAYSTATE HEALTH SYSTEM AS WELL AS SERVING RESEARCHERS FROM ADDITIONAL INSTITUTIONS. 214794 1 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 X 10 10 0 0 0 0 0 1 0 1 1 0 0 1 1 0 0 0 0 0 0 0 MA X LAURIE MARTIN 4137940000 BAYSTATE HEALTH INC 280 CHESTNUT ST SPRINGFIELD MA 01199 X PETER REINHART PHD CHAIR THRU 11/24 THEN VICE CHAIR 5.00 X X 0 0 0 PETER FRIEDMANN VICE CHAIR; DIRECTOR (END 12/24/2024) 5.00 X X 0 0 0 ANDREW MANGELS DIRECTOR 5.00 X 0 0 0 KEITH PARENT DIRECTOR 5.00 X 0 0 0 JAY STEINGRUB DIRECTOR 5.00 X 0 0 0 LAURA VANDENBERG DIRECTOR 5.00 X 0 0 0 D JOSEPH JERRY DIRECTOR; EX-OFFICIO 5.00 X 0 0 0 ASHRAF KHAN MD DIRECTOR 5.00 X 0 0 0 TASHANNA MYERS MD DIRECTOR 5.00 X 0 0 0 JENNIFER SABBAGH PEIRCE CHAIR (START 4/2025) 5.00 X X 0 0 0 MIKE MALONE MD DIRECTOR 5.00 X 0 0 0 RAYMOND MCCARTHY CFO (END 4/2025) 5.00 X 0 0 0 LAURIE MARTIN CFO (START 2/2025) 5.00 X 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5700 5700 13569 13569 69440 69440 145354 145354 234063 214794 19269 0 317025 297199 3887941 3791132 242163 96809 196927 196927 756115 590935 3193 2035 332328 402369 335521 404404 X 420594 186531 420594 186531 756115 590935 -234063 0 X 0 0 0 X 145961 78598 81240 82298 388097 145961 78598 81240 82298 388097 388097 22 22 388119 0.99990 0.99990 X 3304577 3207768 96809 583364 583364 0 96809 DUE FROM RELATED PARTY 196927 196927 DUE TO RELATED PARTY 402369 402369 FORM 990, PART VI, SECTION A, LINE 7A CEO OF BAYSTATE HEALTH, INC. AND PRESIDENT OF UNIVERSITY OF MASSACHUSETTS EACH SELECT 3 DIRECTORS. FORM 990, PART VI, SECTION B, LINE 11B THE FORM 990 IS REVIEWED IN DETAIL BY THE FINANCE AND AUDIT COMMITTEE AND THEREAFTER MADE AVAILABLE TO THE ENTIRE BOARD OF DIRECTORS. FORM 990, PART VI, SECTION B, LINE 12 ALL DIRECTORS ARE REQUIRED TO DISCLOSE ANY CONFLICT AT THE TIME THE CONFLICT ARISES AND REFRAIN FROM PARTICIPATING IN ANY DECISION REGARDING THAT INTEREST. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION MAKES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS AVAILABLE UPON REQUEST PART VI: SECTION B, GOVERNING POLICIES A POLICY HAS BEEN DRAFTED THAT REQUIRES THE ORGANIZATION TO FOLLOW THE GOVERNING POLICIES OF BAYSTATE HEALTH, INC. & UMASS AMHERST, INC.