2026-04-09T16:10:25-07:00 2025-12-31 990 2025-01-01 383903952 THE CENTER FOR ADVANCING INNOVATION INC CENT 2024382208 9508 BURNING TREE RD BETHESDA MD 20817 Cody Locke Chief Innovation Officer 2565063733 2026-02-27 2025 2025-03-06 01:10:19Z Rosemarie Truman 9508 Burning Tree Rd Bethesda MD 20817 13076 0 X www.centerforadvancinginnovation.com X 2012 MD THE CENTER FOR ADVANCING INNOVATION (CAI) IS A GLOBAL PUBLIC-PRIVATE PARTNERSHIP NON-PROFIT FOCUSED ON CREATING A VIRTUOUS CIRCLE OF INNOVATION AND DRIVING GROWTH BREAKTHROUGHS THROUGH NOVEL, CREATIVE PARADIGMS AND MODELS. CAI'S MISSION IS TO ACCELERATE AND INCREASE THE VOLUME OF RESEARCH COMMERCIALIZATION IN SUPPORT OF HIGH GROWTH BUSINESS IN ORDER TO IGNITE ENTREPRENEURSHIP, BOLSTER THE GLOBAL ECONOMY AND MAXIMIZE THE COMMERCIAL AND KNOWLEDGE-BASED POTENTIAL OF PROMISING INVENTIONS. CAI'S AWARD-WINNING CHALLENGE-BASED ACCELERATOR, RIGOROUS FACT-BASED DUE DILIGENCE AND CAPITAL EFFICIENT LEAN MANAGEMENT MODELS SERVE TO HYPER-ACCELERATE "GAZELLE" HIGH- PERFORMING STARTUPS FOR OUTSIZED INVESTOR RETURNS. 4 3 2 12 0 0 0 0 408152 0 24671 13076 0 0 432823 13076 0 0 0 0 564609 389251 0 0 0 146616 61746 711225 450997 -278402 -437921 875820 299168 0 0 875820 299168 X THE CENTER FOR ADVANCING INNOVATION (CAI) IS A GLOBAL PUBLIC-PRIVATE PARTNERSHIP NON-PROFIT FOCUSED ON CREATING A VIRTUOUS CIRCLE OF INNOVATION AND DRIVING GROWTH BREAKTHROUGHS THROUGH NOVEL, CREATIVE PARADIGMS AND MODELS. CAI'S MISSION IS TO ACCELERATE AND INCREASE THE VOLUME OF RESEARCH COMMERCIALIZATION IN SUPPORT OF HIGH GROWTH BUSINESS IN ORDER TO IGNITE ENTREPRENEURSHIP, BOLSTER THE GLOBAL ECONOMY AND MAXIMIZE THE COMMERCIAL AND KNOWLEDGE-BASED POTENTIAL OF PROMISING INVENTIONS. CAI'S AWARD-WINNING CHALLENGE-BASED ACCELERATOR, RIGOROUS FACT-BASED DUE DILIGENCE AND CAPITAL EFFICIENT LEAN MANAGEMENT MODELS SERVE TO HYPER-ACCELERATE "GAZELLE" HIGH- PERFORMING STARTUPS FOR OUTSIZED INVESTOR RETURNS. 1 0 98553 0 0 The Global Health Innovation Challenge II (GHIC II) is orchestrated by the Center for Advancing Innovation (CAI) with support from the United States Economic Development Administration (EDA) Build to Scale (B2S) Program. As with CAI's prior challenges, teams will advance promising de-risked inventions selected with rigorous due diligence by potential investors and industry experts. Teams may also enter with their own commercially-viable inventions. CAI invites anyone to submit an idea with the potential to hyper-accelerate the future of health. An expert judging panel will select winners from the pool of teams, advancing promising inventions. 0 0 0 98553 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 X 4 3 0 0 0 0 0 0 0 1 0 0 0 1 1 1 1 1 1 1 1 0 DC MD VA X X ROSEMARIE TRUMAN 2024382208 9508 BURNING TREE RD BETHESDA MD 20817 ROSEMARIE TRUMAN CEO 40 0 X X 170250 0 0 CODY LOCKE CHIEF INNOVATION OFFICER 40 0 X 170250 0 0 NICK DONOFRIO CHAIRMAN 0 0 X 0 0 0 GIL PRICE DIRECTOR 0 0 X 0 0 0 REGINALD SEETO DIRECTOR 0 0 X 0 0 0 340500 0 0 2 0 1 0 0 0 0 13076 13076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13076 13076 0 0 340500 340500 22677 22677 26074 26074 41 41 11903 11903 14595 14595 7431 7431 5870 5870 8089 8089 7409 7409 5713 5713 Membership and subscription fees 695 695 0 0 450997 98553 352444 0 381386 299168 854 493580 875820 299168 0 0 0 0 0 0 X 875820 299168 0 0 875820 299168 875820 299168 X -437921 0 0 0 0 -138731 X 0 0 0 X 43093 276974 320067 277074 342000 265424 408152 1292650 320167 618974 265424 408152 0 1612717 1612717 281 18461 44139 24671 13076 100628 281 18461 44139 24671 13076 100628 320448 637435 309563 432823 13076 1713345 0.94127 0.97632 0.05873 0.02368 X Schedule A, Part III, Line 12 The organization qualifies as a publicly supported organization under IRC Section 509(a)(2). Public support consists primarily of contributions and program-related receipts. Investment income reported consists of interest earned on cash held in a money market account and does not exceed the applicable limitations. X 0 0 0 0 0 0 0 0 0 ROSEMARIE TRUMAN CEO 170250 0 0 0 0 0 0 0 0 0 170250 0 0 0 CODY LOCKE CHIEF INNOVATION OFFICER 170250 0 0 0 0 0 0 0 0 0 170250 0 0 0 Form 990, Part III, Line 2 In 2025, CAI launched and publicly announced the Future of Health Innovation Tournament Challenge (FHITC), a new global competition and accelerator program designed to source, mentor, and launch more than 15 high-growth startups at the intersection of biotechnology, medical technology, genomics, synthetic biology, artificial intelligence (AI), and quantum computing. The FHITC operates as both a tournament and a challenge over a twelve-month period, provides targeted entrepreneurial training and access to CAI's accelerator resources, engages entrepreneurs, subject-matter experts, and interns worldwide, and aims to accelerate commercialization, create knowledge-based jobs, and raise investment capital for participating teams. FHITC was announced publicly on October 23, 2025. Form 990, Part VI, Section A, Line 8b The organization does not maintain separate committees with authority to act on behalf of the governing body. All governance actions are documented at the board level. Form 990, Part VI, Section B, Line 11b A complete draft of Form 990 was provided to each member of the governing body prior to filing. Directors were given the opportunity to review the return and provide comments before submission. Form 990, Part VI, Section B, Line 12c The organization monitors compliance with its conflict of interest policy through annual disclosures and review by the board of directors, with any conflicts addressed and documented as needed. Form 990, Part VI, Section B, Line 15 Compensation for the CEO and other officers or key employees is reviewed and approved by independent members of the governing body using comparability data and is contemporaneously documented. The process was last undertaken in 2025. Form 990, Part VI, Section C, Line 19 The organization's governing documents, conflict of interest policy, and financial statements are available to the public upon request. Form 990, Part XI, Line 9 Decrease reflects balance-sheet movements including liquidation of prior-year investments, inter-account transfers, and timing differences between operating cash usage and prior-period asset balances. These amounts do not represent current-year expenses or revenue.