2025-10-30T03:16:55-07:00 2024-12-31 270741376 HARSHWAL & COMPANY LLP 11405 W BERNARDO CT STE A SAN DIEGO CA 92127 990 2024-01-01 943308627 SUSTAINABLE SCIENCES INSTITUTE SUST 5108174949 1212 PRESERVATION PARK WAY SUITE 30 OAKLAND CA 94612 Josefina Coloma Executive Director 2025-10-30 true true Sanwar Harshwal CPA P01249746 8589390017 X 2024 2025-03-06 01:10:19Z Josefina Coloma 3292396 false X WWW.SUSTAINABLESCIENCES.ORG X 1998 CA THE ORGANIZATION PROVIDES TO THE DEVELOPING WORLD WITH TECHNICAL TRAINING,TOOLS AND SUPPLIES AND ONGOING COACHING TO HEALTH PROFESSIONALS AND SCIENTISTS. 10 10 4 0 3176927 3286610 0 1364 1614 339 4172 3178630 3292396 13867 71660 0 2009130 1962717 0 0 1245404 1214275 3268401 3248652 -89771 43744 1819647 1608690 988750 734049 830897 874641 X THE SUSTAINABLE SCIENCES INSTITUTE (DUNS XXX-XX-XXXX, EIN XXX-XX-XXXX) IS A 501C(3) INCORPORATED IN SAN FRANCISCO, CALIFORNIA IN 1998. SSI IS DEDICATED TO DEVELOPING ENDOGENOUS SCIENTIFIC RESEARCH CAPACITY IN RESOURCE-POOR SETTINGS WITH PRESSING HEALTH PROBLEMS. TO THIS END, SSI PROVIDES UNIQUE PROGRAMS TO DEVELOP AND SUPPORT SCIENTIFIC AND PUBLIC HEALTH COMMUNITIES AND SYSTEMS. SUBSIDIARIES OF SSI ARE INCORPORATED IN NICARAGUA (2004) AND EGYPT (2011). THERE IS ONE BOARD OF DIRECTORS LOCATED IN SAN FRANCISCO. ALL FUNDS ARE ADMINISTERED THROUGH SSI'S SAN FRANCISCO HEADQUARTERS WITH NICARAGUAN AND EGYPTIAN FIELD COMPONENTS IMPLEMENTED BY LOCAL STAFF.SSI'S PRESIDENT, EVA HARRIS PHD (PROFESSOR OF IMMUNOLOGY AND INFECTIOUS DISEASE, UNIV. OF CALIFORNIA, BERKELEY) BEGAN SSI'S FOUNDATIONAL WORK IN 1988 UNDER THE APPLIED MOLECULAR BIOLOGY/APPROPRIATE TECHNOLOGY TRANSFER PROGRAM AND WAS AWARDED A MACARTHUR GENIUS FELLOWSHIP IN 1997. SSI'S VICE PRESIDENT, DR. ED WAKIL (DIRECTOR, SAN FRANCISCO true false 2353204 4398 RESEARCH ON INFECTIOUS DISEASE IN NICARAGUASSI CARRIES OUT RESEARCH ON INFECTIOUS DISEASES IN NICARAGUA WITH COMMITTED RESEARCH FUNDING OF APPROXIMATELY $7 MILLION OVER THE NEXT THREE YEARS FROM GOVERNMENT SOURCES (NATIONAL INSTITUTES OF HEALTH, CENTERS FOR DISEASE CONTROL AND PREVENTION, US AGENCY FOR INTERNATIONAL DEVELOPMENT) VIA DIRECT AWARDS AND SUBCONTRACTS FROM LARGE RESEARCH UNIVERSITIES (UNIVERSITY OF CALIFORNIA, COLORADO STATE UNIVERSITY, UNIVERSITY OF MICHIGAN, MT. SINAI SCHOOL OF MEDICINE, STANFORD UNIVERSITY). SSI ALSO RECEIVES FUNDING FROM PRIVATE FOUNDATIONS (IBRAHIM EL-HEFNI TECHNICAL TRAINING FOUNDATION, BILL AND MELINDA GATES FOUNDATION, INSTITUTO SLIM PARA LA SALUD, UBS OPTIMUS FOUNDATION) AND CONTRACTS FROM SMALLER PRIVATE ORGANIZATIONS (SEVIDENT, PAXVAX).IN 2016, THE ZIKA PANDEMIC HIT LATIN AMERICA, INCLUDING OUR SITE IN NICARAGUA, REVEALING ZIKA'S RELATIONSHIP TO DEVASTATING CONGENITAL BIRTH DEFECTS.IN COLLABORATION WITH NICARAGUAN COLLEAGUES, SSI REFOCUSED ITS EXISTING DENGUE AND CHIKUNGUNYA RESEARCH TO ADDRESS URGENT QUESTIONS ABOUT ZIKA; EFFORTS TO DEVELOP AND EVALUATE NEW DIAGNOSTIC AND RESEARCH TECHNIQUES WERE INCORPORATED INTO EXISTING HOSPITAL AND COHORT STUDIES. SSI ALSO LAUNCHED STUDIES OF ZIKA'S INCIDENCE AND HOUSEHOLD TRANSMISSION PATTERNS, A LONGITUDINAL STUDY OF ZIKA IN PREGNANT WOMEN AND INFANTS, AND AN INNOVATIVE COMMUNITY-BASED INTERVENTION FOR ZIKA PREVENTION. THIS INTEGRATED APPROACH ENABLES STUDY OF ZIKA'S CLINICAL ASPECTS, EPIDEMIOLOGICAL AND IMMUNOLOGICAL RESPONSES, MODELING OF THE INTERACTIONS BETWEEN IMMUNE RESPONSES, AND EXPANSION OF COMMUNITY-BASED EFFORTS TO PREVENT ZIKA AS WELL AS DENGUE. THIS RESEARCH CONTINUES TO SHOWCASE OUR COLLABORATING SITE IN NICARAGUA WHICH HAS BECOME INTERNATIONALLY RENOWNED FOR ARBOVIRUS DIAGNOSIS, RESEARCH AND EPIDEMIOLOGY.IN NICARAGUA, SSI'S STUDIES HAVE RECEIVED FAVORABLE NATIONAL PRESS, STRONG GOVERNMENT SUPPORT, AND HIGH REGARD WITHIN THE COMMUNITIES WHERE WORK IS CONDUCTED.FOR THE LAST TEN YEARS, SSI HAS BEEN WORKING TOWARDS UNDERSTANDING THE EPIDEMIOLOGY AND CLINICAL PRESENTATION OF INFLUENZA AND OTHER RESPIRATORY VIRUS INFECTIONS IN NICARAGUA. IN LATE 2015, SSI-NICARAGUA WAS SELECTED AS ONE OF FOUR SITES TO CONDUCT A CDC-FUNDED STUDY EXAMINING INFLUENZA PREVENTION AMONG INFANTS THROUGH VACCINATION. THIS STUDY, AND ANOTHER EXAMINING INFLUENZA TRANSMISSION WITHIN HOUSEHOLDS, ARE CONDUCTED IN CLOSE COLLABORATION WITH THE NICARAGUAN MINISTRY OF HEALTH AND THE UNIVERSITY OF MICHIGAN. SSI RECEIVES CONTINUED SUPPORT OF ITS INFLUENZA COHORT STUDY FROM THE NIH CENTER OF EXCELLENCE FOR INFLUENZA RESEARCH AND SURVEILLANCE AT THE ST. JUDE CHILDREN'S RESEARCH HOSPITAL.SSI, IN COLLABORATION WITH THE NICARAGUAN MINISTRY OF HEALTH AND THE UNIV. OF CALIFORNIA AT BERKELEY, CONTINUES TO OPERATE THE PEDIATRIC DENGUE COHORT STUDY (NOW IN ITS 14TH YEAR) AND THE HOSPITAL-BASED STUDY (NOW IN ITS 20TH YEAR) IN MANAGUA. THESE COHORT STUDIES SUPPLY THE INFRASTRUCTURE AND BIOREPOSITORY THAT ALLOWS SSI AND ITS PARTNERS TO BE LEADERS IN GLOBAL ARBOVIRUS RESEARCH. EACH YEAR APPROXIMATELY 3,600 CHILDREN PARTICIPATE PROVIDING INVALUABLE BIOLOGICAL SAMPLES USED TO STUDY DETERMINANTS OF PROTECTION FROM, AND RISK OF, DENGUE, ZIKA AND CHIKUNGUNYA DISEASE. IN 2017, OUR RESEARCH RESULTED IN A NUMBER OF HIGH-IMPACT PUBLICATIONS AND SCIENTIFIC PRESENTATIONS. SSI IS ADAPTING ITS DENGUECHAT TOOL FOR COMMUNITY-BASED RESEARCH ON ZIKA. THE DENGUECHAT TOOL, DEVELOPED AT UNIV. OF CALIFORNIA AT BERKELEY, IS A FREE TECHNOLOGY THAT SUPPORTS COMMUNITY-LEVEL MOSQUITO CONTROL EFFORTS. THE PLATFORM ALLOWS A HEALTH TEAM - BRIGADISTAS DE SALUD Y VIDA - TO CAPTURE ENTOMOLOGICAL DATA, VISUALIZE HIGH-RISK AREAS, AND MEASURE IMPACT OVER TIME. DENGUECHAT EMPOWERS THE COMMUNITY TO PRODUCE AND SYSTEMATIZE LOCAL, REAL-TIME DATA TO MAKE DECISIONS ABOUT MOSQUITO CONTROL TO PREVENT DENGUE, CHIKUNGUNYA AND ZIKA. THE PLATFORM'S BLOG ALLOWS COMMUNITY BRIGADES TO CONNECT, COMPETE, AND SHARE INFORMATION ENCOURAGING THEM TO BECOME KEY MOTIVATORS IN COMMUNITY MOBILIZATION AND HEALTH PROMOTION EFFORTS. IN THE FIVE COMMUNITIES WHERE DENGUECHAT WAS PILOTED, SIGNIFICANT REDUCTION IN MOSQUITO INFESTATION WAS MEASURED. WE ARE ADAPTING THIS PLATFORM TO ZIKA WITH THE AIM MONITORING VECTOR INFESTATION AND TRACKING ZIKA RISK IN MANAGUA'S URBAN AND RURAL NEIGHBORHOODS. 101751 67262 ECUADOR PROGRAMS -In Ecuador, SSI provided technical, logistical and monetary support to develop alaboratory at INSPI (Instituto Nacional de Investigacion Salud Publica). Inaddition, SSI launched BIENSUR, a comprehensive care program to improveindigenous Ecuadorian womens health outcomes and well-being. A successful 2024pilot reached 50 urban, migrant, indigenous women integrating sexual andreproductive healthcare (SRH) including HPV treatment, mental resilience training,gender violence prevention (GBV), and community empowerment. SSI also providedscholarships for several students to complete their degrees at the SalesianUniversity, Quito, Ecuador. 8000 CAPACITY-BUILDING WORKSHOPSLED BY SSI'S SCIENTIFIC DIRECTOR, MARIA ELENA PENARANDA PHD, SSI'S CAPACITY-BUILDING PROGRAM TRAINS AND TRANSFERS TECHNOLOGIES TO NASCENT SCIENTISTS AND HEALTH PROFESSIONALS AROUND THE WORLD VIA IN-COUNTRY, SHORT-TERM, INTENSIVE HANDS-ON WORKSHOPS. WORKSHOPS ARE FUNDED BY GOVERNMENT CONTRACTS, NON-GOVERNMENTAL ORGANIZATIONS, SCIENTIFIC INSTITUTIONS, UNIVERSITIES, PRIVATE FOUNDATIONS AND INDIVIDUAL DONORS. WORKSHOP TOPICS INCLUDE: TECHNIQUES FOR COST-EFFECTIVE DIAGNOSIS AND EPIDEMIOLOGICAL ANALYSIS OF REGION-ENDEMIC INFECTIOUS DISEASES, RESEARCH DESIGN, MANUSCRIPT WRITING FOR PUBLICATION, AS WELL AS PROPOSAL WRITING AIMED AT HELPING SCIENTISTS CRYSTALIZE THEIR IDEAS AND SUCCESSFULLY APPLY FOR LARGER FUNDING OPPORTUNITIES.SSI ENGAGES TALENTED BIOMEDICAL SCIENTISTS AND PROGRAM DIRECTORS AND BY EXTENSION THEIR INSTITUTIONS - TO SERVE AS LOCAL TRAINERS AND MENTORS.USING THIS "TRAIN THE TRAINERS" APPROACH, SSI HAS DEVELOPED A NETWORK OF EXPERIENCED PEER TRAINERS AND TUTORS THAT HAS CONDUCTED OVER 100 WORKSHOPS AND TRAINED MORE THAN 2,500 HEALTH RESEARCHERS FROM 33 LOW INCOME COUNTRIES IN AFRICA, ASIA AND THE AMERICAS.THIS "TRAIN THE TRAINERS" MODEL, COMBINED WITH OUR LONG-TERM COMMITMENT, HAS BUILT ENDURING AND RESILIENT NETWORKS THAT EXPAND REGIONAL CAPACITY TO CONDUCT CLINICAL AND BASIC RESEARCH, DEVELOP CRITICAL SKILLS AND KNOWLEDGE BASE AMONG COLLEAGUES, AND SUPPORT REGIONAL SCIENTISTS TO EFFECT REAL CHANGE IN THE HEALTH OF THEIR COMMUNITIES. SSI'S WORK IS RECOGNIZED AS A MODEL FOR TECHNOLOGY TRANSFER AND CAPACITY BUILDING BY THE WORLD HEALTH ORGANIZATION (WHO), PAN AMERICAN HEALTH ORGANIZATION (PAHO), U.S. NATIONAL SCIENCE FOUNDATION, U.S. NATIONAL ACADEMY OF SCIENCES, THE GATES FOUNDATION, AND THE MINISTRIES OF HEALTH IN SEVERAL COUNTRIES.IN 2017, SSI TRAINED 116 HEALTH PROFESSIONALS IN SIX CAPACITY-BUILDING WORKSHOPS ON LABORATORY TECHNIQUES, SCIENTIFIC WRITING AND RESEARCH PROPOSAL PREPARATION. THE CENTER FOR EMERGING AND NEGLECTED DISEASES (CEND) INVITED SSI TO TEACH A PROPOSAL WRITING WORKSHOP FOR MASTER'S AND DOCTORAL STUDENTS AT MAKERERE UNIVERSITY IN KAMPALA, UGANDA. DUE TO SSI'S EXPERIENCE IMPLEMENTING THE LATEST TECHNIQUES FOR DETECTING AND DIAGNOSING ZIKA, DENGUE AND CHIKUNGUNYA VIRUSES, SSI ALSO RECEIVED A GRANT FROM THE CONSERVATION FOOD AND HEALTH FOUNDATION (CFHF) TO CONDUCT LABORATORY TRAINING IN CENTRAL AMERICA. THE WORKSHOP TOOK PLACE IN HONDURAS, WITH PARTICIPATION OF SCIENTISTS FROM PANAMA, NICARAGUA, EL SALVADOR, HONDURAS AND GUATEMALA. 2462955 true true false false false false false false false false true false false false true false true false false true true true false false false false false false false false false false false false false false false false false false false false false false false false false true 7 0 true 4 true false true NU false false false false false 0 false false false false false false false X 10 10 false false false false false false false true true false true true true true true true true true true true false CA X MARLON BUITRAGO 5108174949 1212 PRESERVATION PARK WAY SUITE 30 OAKLAND CA 94612 X Josefina Coloma Executive Director 8.00 0.00 53685 0 0 EVA HARRIS PHD President 1.00 0.00 X X 0 0 0 ADIL ED WAKIL MD Vice President 1.00 0.00 X X 0 0 0 P ROBERT BEATTY PHD Secretary 1.00 0.00 X X 0 0 0 JONATHAN CRONANDER Treasurer 1.00 0.00 X X 0 0 0 JANE L GROGAN PHD Director 1.00 0.00 X 0 0 0 JIM LARRICK MD PHD Director 0.50 0.00 X 0 0 0 STEPHEN POPPER DSC Director 0.50 0.00 X 0 0 0 DR LISA DANZIG Director 0.50 0.00 X 0 0 0 LELAND YEE Director 0.50 0.00 X 0 0 0 53685 0 false false false 0 3153065 133545 3286610 0 1614 1614 0 0 0 0 0 0 0 Other Income 4172 4172 4172 3292396 5786 0 0 71660 71660 0 53685 53685 0 1490855 1320914 169941 0 119223 117692 1531 298954 281036 17918 0 0 25492 25492 0 0 0 154346 97384 56962 0 11849 11849 0 0 51020 1578 49442 30782 30782 0 38379 38379 7039 5498 1541 0 244191 219500 24691 4476 4476 Supplies 432030 197286 234744 Vehicle Expenses 65701 65701 Telephone and communication 48467 47364 1103 Equipment and maintenance 37564 37564 62939 33882 29057 3248652 2462955 785697 0 431187 614683 0 0 633513 428132 0 0 0 0 2244 0 1383469 1032528 427360 350941 0 0 0 323175 212766 2168 2168 1819647 1608690 440648 429905 222057 89030 326045 215114 988750 734049 X 805897 849641 25000 25000 830897 874641 1819647 1608690 43744 X false true X false true true X 2783325 2730239 3929455 3176927 3286610 15906556 0 0 2783325 2730239 3929455 3176927 3286610 15906556 0 15906556 6513 335 4723 1364 1614 14549 0 339 4172 4511 15925616 0.99880 0.99820 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 101320 101320 139919 42007 97912 938361 827322 111039 203869 163199 40670 350941 Operating Lease Liabilities 215114 215114 3292396 3292396 3292396 3248652 3248652 3248652 Central America & Caribbea 1 90 Program Services/Grants Dengue, Influenza, Zika, COVID 2462955 1 90 1 90 2462955 2462955 Cnt Amrca & Crb Non-Labour Expense 71659 Wire Transfe 1 false false false false false false Form 990, Part III, Line 2 ECUADOR PROGRAMS INTRODUCE DURING THE CURRENT YEAR. Form 990, Part VI, Section B, Line 11b AN ELECTRONIC COPY OF THE FORM 990 IS SENT TO ALL BOARD MEMBERS (SSI'S GOVERNING BODY) BEFORE IT IS FILED. ADDITIONALLY, ALL MEMBERS ARE ASKED TO REVIEW AND APPROVE, VIA EMAIL, THE FORM 990 BEFORE IT IS FILED. Form 990, Part VI, Section B, Line 12c ALL DIRECTORS/OFFICERS/ELIGIBLE EMPLOYEES ARE REQUIRED TO REVIEW AND RESIGN THE CONFLICT OF INTEREST POLICY ANNUALLY. ANY CONFLICTS OF INTEREST OR SUSPECTED VIOLATIONS OF THE POLICY ARE INVESTIGATED AND DEALT WITH ACCORDINGLY BY THE BOARD. Form 990, Part VI, Section B, Line 15b SSI WRITTEN EMPLOYEE EVALUATIONS ARE DONE ANNUALLY BY THE NON-SALARIED EXECUTIVE COMMITTEE (PRESIDENT, VICE PRESIDENT, SECRETARY, AND TREASURER)OF THE BOARD OF DIRECTORS. EACH EMPLOYEE COMPLETES A WRITTEN SELF-EVALUATION; THE EXECUTIVE COMMITTEE ALSO WRITES AN EVALUATION OF THE EMPLOYEE AND THEN MEETS WITH EACH EMPLOYEE TO DISCUSS HIS/HER PERFORMANCE OVER THE YEAR. THE COMMITTEE THEN DELIBERATES AND RECOMMENDS EACH EMPLOYEE'S MERIT AND COST OF LIVING INCREASES TO THE BOARD. THE BOARD APPROVES (OR CHANGES) THE INCREASES, WITH THE DECISION BASED ON EMPLOYEE PERFORMANCE, SSI FINANCIAL HEALTH, AND A COMPARISON TO PAY FOR SIMILAR POSITIONS AT OTHER NONPROFITS IN THE BAY AREA. Form 990, Part VI, Section C, Line 19 ALL GOVERNING DOCUMENTS, THE CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS ARE AVAILABLE TO THE PUBLIC ON THE SSI WEBSITE AND/OR IN OUR OAKLAND OFFICE DURING REGULAR BUSINESS HOURS.