2025-06-26T07:49:43-05:00 2024-12-31 471096596 RAFFOL AND COMPANY INC 105 CHESTNUT ST SUITE 11 NEEDHAM MA 02492 990 2024-01-01 845157239 POLYBIO RESEARCH FOUNDATION INC POLY 9178480238 47 HIGH STREET SUITE 403 MEDFORD MA 02155 AMY PROAL PRESIDENT 9178480238 2025-06-26 1 1 JONATHAN VITALE P01922134 7814444926 2025-06-23 2024 2025-03-06 01:10:19Z AMY PROAL 47 HIGH STREET SUITE 403 MEDFORD MA 02155 4324689 0 X HTTPS://POLYBIO.ORG/ X 2020 WA WE ARE A 501(C)3 TRANSFORMING HOW COMPLEX CHRONIC CONDITIONS LIKE LONGCOVID, ME/CFS & POST TREATMENT LYME DISEASE ARE STUDIED, DIAGNOSED, AND TREATED. POLYBIO WAS FOUNDED BY THREE SCIENTISTS WITH COMPLEMENTARY EXPERTISE (NEUROSCIENCE, MICROBIOLOGY & GENETICS). WE CONCEPTUALIZE RESEARCH PROJECTS THAT IDENTIFY ROOT CAUSE DRIVERS OF THESE CONDITIONS AND BUILD COLLABORATIVE TEAMS TO MAKE THE PROJECTS A REALITY. 6 6 1 5 0 0 17350488 4095453 0 0 0 229236 0 0 17350488 4324689 18250077 13813525 0 0 142327 193605 0 0 27634 242216 134882 18634620 14142012 -1284132 -9817323 15536208 9811535 2622925 6715575 12913283 3095960 X WE ARE A 501(C)3 TRANSFORMING HOW COMPLEX CHRONIC CONDITIONS LIKE LONGCOVID, ME/CFS & POST TREATMENT LYME DISEASE ARE STUDIED, DIAGNOSED, AND TREATED. POLYBIO WAS FOUNDED BY THREE SCIENTISTS WITH COMPLEMENTARY EXPERTISE (NEUROSCIENCE, MICROBIOLOGY & GENETICS). WE CONCEPTUALIZE RESEARCH PROJECTS THAT IDENTIFY ROOT CAUSE DRIVERS OF THESE CONDITIONS AND BUILD COLLABORATIVE TEAMS TO MAKE THE PROJECTS A REALITY. 0 0 14046841 13813525 WE CONCEPTUALIZE COLLABORATIVE RESEARCH PROJECTS ON ME/CFS, LONGCOVID AND RELATED INFECTION-ASSOCIATED CHRONIC CONDITIONS. OUR PROJECTS STUDY "ROOT CAUSE" DRIVERS OF THESE CONDITIONS, AND COMBINE THE SKILLS OF VIROLOGISTS, NEUROSCIENTISTS, PATHOLOGISTS, MICROBIOME EXPERTS AND PATIENT ADVOCATES TO MAXIMIZE IMPACT. 14046841 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 1 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 4 0 1 1 0 0 0 0 0 0 0 0 0 0 X 6 6 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 MA X ADEEL IRSHAD 6178070786 245 FIRST STREET RIVERVIEW II SUITE CAMBRIDGE MA 02142 AMY PROAL EXECUTIVE DIRECTOR 40.00 X X 185000 0 0 MICHAEL VANELZAKKER DIRECTOR 3.00 X X 0 0 0 CHARLOTTE MAO CLERK 3.00 X X 0 0 0 MARK LONGSTRETH TREASURER 2.00 X X 0 0 0 MAGGIE STEFFENS DIRECTOR 1.00 X X 0 0 0 KATHRYN BACH DIRECTOR 3.00 X X 0 0 0 FRANCIS BRENNER CHAIR 3.00 X X 0 0 0 185000 0 0 1 0 1 0 0 4095453 4095453 229236 229236 4324689 0 0 229236 11910094 11910094 60000 60000 1843431 1843431 181154 126808 36231 18115 12451 8716 2490 1245 33753 6751 23627 3375 7555 2267 2644 2644 4837 1935 1451 1451 9679 8711 484 484 965 579 338 48 WEBSITE 57775 57775 PROJECT EXPENSES 14875 14875 TELEPHONE AND INTERNET 5443 4899 272 272 14142012 14046841 67537 27634 14418113 1936121 7340133 1118095 535281 15536208 9811535 2619336 6714063 3589 1512 2622925 6715575 X -1894901 -5145307 14808184 8241267 12913283 3095960 15536208 9811535 -9817323 0 X 0 0 0 X 24211 622734 1208853 2416238 4095453 8367489 24211 622734 1208853 2416238 4095453 8367489 4913406 3454083 8367489 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 PAYROLL LIABILITIES 1512 1512 4324689 0 4324689 0 4324689 14142012 0 14142012 0 14142012 0 0 0 0 0 0 0 0 0 0 EUROPE RESEARCH GRANT 252366 0 EUROPE RESEARCH GRANT 391500 0 EUROPE RESEARCH GRANT 600000 0 EUROPE RESEARCH GRANT 500000 0 AFRICA RESEARCH GRANT 99565 0 0 0 0 0 0 0 0 AMICI LOVANIENSES 6465 ALMADEN EXPRESSWAY SAN JOSE CA 95120 159128 0 RESEARCH GRANT ARIZONA STATE UNIVERSITY FOUNDATION FOR A NEW AMERICAN UNIVERSITY PO BOX 2260 TEMPE AZ 85280 345000 0 RESEARCH GRANT BRIGHAM AND WOMENS HOSPITAL 75 FRANCIS STREET BOSTON MA 02115 93128 0 RESEARCH GRANT GEORGETOWN UNIVERSITY 37TH O STREETS NW WASHINGTON DC 20057 129305 0 RESEARCH GRANT ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI 1 GUSTAVE LEVY BOX 1075 NEW YORK NY 10029 3503518 0 RESEARCH GRANT J CRAIG VENTER INSTITUTE 4120 CAPRICORN LANE LA JOLLA CA 92037 290025 0 RESEARCH GRANT NYU GROSSMAN SCHOOL OF MEDICINE 550 FIRST AVENUE NEW YORK NY 10016 999812 0 RESEARCH GRANT REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO 1855 FOLSOM ST STE 425 SAN FRANCISCO CA 94103 3203968 0 RESEARCH GRANT STANFORD UNIVERSITY 450 JANE STANFORD WAY STANFORD CA 94305 57330 0 RESEARCH GRANT STRATEVI LLC ONE LINCOLN ST 29TH FLOOR BOSTON MA 02111 201000 0 RESEARCH GRANT UMASS CHAN MEDICAL SCHOOL 55 LAKE AVENUE NORTH WORCESTER MA 01655 250000 0 RESEARCH GRANT UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE 5TH FLOOR FRANKLIN BUILDING 3451 WALNUT STREET PHILADELPHIA PA 19104 2091756 0 RESEARCH GRANT UNIVERSITY OF TEXAS SOUTHWESTERN 5323 HARRY HINES BLVD DALLAS TX 75390 11124 0 RESEARCH GRANT YALE UNIVERSITY 150 MUNSON STREET 25 SCIENCE PARK NEW HAVEN CT 06520 575000 0 RESEARCH GRANT RESEARCH GRANT 1 60000 X 0 0 0 0 0 0 0 0 0 AMY PROAL EXECUTIVE DIRECTOR 185000 0 0 0 0 0 0 0 0 0 185000 0 0 0 MICHAEL VANELZAKKER - MASS GENERAL BRIGHAM BOARD MEMBER GRANT CHRONIC DISEASE RESEARCH KATHRYN BACH BOARD MEMBER 20000 GRANT CONSULTANT FORM 990, PART VI, SECTION B, LINE 11B THE ORGANIZATION'S PRESIDENT, TREASURER AND OUTSOURCED ACCOUNTING FIRM PERFORM A DETAILED REVIEW OF THE FORM 990. ONCE APPROVED, A COPY OF THE FINAL FORM 990 IS PROVIDED TO ALL OTHER BOARD MEMBERS PRIOR TO BEING FILED WITH THE IRS. FORM 990, PART VI, SECTION B, LINE 12C THE BOARD HAS APPROVED A CONFLICT OF INTEREST POLICY WHICH IS APPLICABLE TO ALL DIRECTORS/TRUSTEES, OFFICERS, MEMBERS OF A COMMITTEE WITH GOVERNING BOARD DELEGATED POWERS, OR SENIOR EMPLOYEES WHO HAVE A DIRECT OR INDIRECT FINANCIAL OR DUALITY INTEREST (COLLECTIVELY, "INTERESTED PERSONS"). THE POLICY REQUIRES INTEREST PERSONS TO DISCLOSE ANY ACTUAL OR POSSIBLE CONFLICTS OF INTEREST AND ALL MATERIAL FACTS TO THE DIRECTORS AND MEMBERS OF COMMITTEES WITH GOVERNING BOARD DELEGATED POWERS CONSIDERING THE PROPOSED TRANSACTION OR ARRANGEMENT. AFTER SUCH DISCLOSURE, THE INTERESTED PERSON MUST LEAVE THE MEETING WHILE THE REMAINING BOARD OR COMMITTEE MEMBERS SHALL DECIDE IF A CONFLICT OF INTEREST ACTUALLY EXISTS, REVIEW ALTERNATIVES, AND VOTE ON WHETHER OR NOT TO APPROVE THE TRANSACTION. IN ADDITION, EACH INTERESTED PERSON IS REQUIRED TO ANNUALLY SIGN A STATEMENT ACKNOWLEDGING THEIR RECEIPT AND UNDERSTANDING OF THE POLICY, THEIR AGREEMENT TO COMPLY WITH THE POLICY, AND PROVIDE INFORMATION RELATED TO ANY ACTUAL OR POSSIBLE CONFLICTS OF INTEREST. FORM 990, PART VI, SECTION B, LINE 15 THE COMPENSATION OF THE ORGANIZATION'S EXECUTIVE DIRECTOR IS DETERMINED BY THE FULL BOARD (EXCEPT FOR THE PRESIDENT SINCE THE PRESIDENT IS ALSO THE EXECUTIVE DIRECTOR). THE TREASURER RESEARCHES COMPENSATION DATA FOR SIMILAR POSITIONS AT SIMILAR ORGANIZATIONS TO DETERMINE THE REASONABLENESS OF THE COMPENSATION. SUCH RESEARCH IS CONTEMPORANEOUSLY DOCUMENTED, AND THE DECISION IS DOCUMENTED IN THE MINUTES OF THE BOARD MEETING. THE ORGANIZATION DOES NOT COMPENSATE ANYONE ELSE MEETING THE DEFINITION OF AN "OFFICER OR "KEY EMPLOYEE," AS DEFINED BY THE IRS. FORM 990, PART VI, SECTION C, LINE 18 UPON REQUEST FORM 990, PART VI, SECTION C, LINE 19 UPON REQUEST