2024-08-15T14:05:50-05:00 2023-09-30 910189318 MOSS ADAMS LLP 3121 W MARCH LN STE 200 STOCKTON CA 952192367 990PF 2022-10-01 845192069 WELLCOME LEAP INC WELL 7033441775 9942 CULVER BLVD 1277 CULVER CITY CA 90232 REGINA DUGAN PRESIDENT & CEO 7034050316 2024-08-14 1 1 TRACY S PAGLIA P00366884 2099556100 2024-08-14 2022 2024-08-08 14:25:15Z X 403398604 X 2359904 710850 710850 0 4692 0 3075446 710850 1157602 0 1236174 4878125 0 4876311 273093 0 235560 163437 0 188228 247402 6185 235850 149242444 0 161017647 205801 0 205801 144370 0 1190785 0 1169425 629373 0 625550 158132432 6185 169790546 480753 480753 158613185 6185 170271299 -155537739 704665 250000 250100 250100 5394360 48441952 48441952 278607708 498247804 278607708 278607708 48645485 75937366 75937366 129679 55172 673568 74507 74507 107042 86971 86971 553318259 403398604 403398604 230519 16908 2202477 8034172 2432996 8051080 X 200221 435010 550685042 394912514 550885263 395347524 553318259 403398604 550885263 -155537739 0 395347524 0 395347524 9795 0 9795 0 9795 0 0 13000 0 13000 101 3104 3104 0 0 0 0 0 0 0 0 0 0 0 1 1 CA DE 1 0 0 0 0 1 WWW.WELLCOMELEAP.ORG RICHARD WOOLDRIDGE COO 9165038105 9942 CULVER BLVD 1277 CULVER CITY CA 90232 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 REGINA DUGAN 9942 CULVER BLVD 1277 CULVER CITY CA 90232 DIRECTOR, PRESIDENT & CEO 40.00 747620 40270 0 JAY FLATLEY 9942 CULVER BLVD 1277 CULVER CITY CA 90232 DIRECTOR & CHAIR 1.00 150000 0 0 MICHAEL FERGUSON 9942 CULVER BLVD 1277 CULVER CITY CA 90232 DIRECTOR 1.00 0 0 0 JEREMY FARRAR 9942 CULVER BLVD 1277 CULVER CITY CA 90232 DIRECTOR 1.00 0 0 0 RACHEL ROGERS 9942 CULVER BLVD 1277 CULVER CITY CA 90232 SECRETARY 40.00 208850 51395 0 KAIGHAM GABRIEL 9942 CULVER BLVD 1277 CULVER CITY CA 90232 COO (THROUGH JULY 2023) 40.00 605769 39210 0 HO CHING 9942 CULVER BLVD 1277 CULVER CITY CA 90232 DIRECTOR 1.00 50000 0 0 FIONA POWRIE 9942 CULVER BLVD 1277 CULVER CITY CA 90232 DIRECTOR 1.00 0 0 0 RICHARD WOOLDRIDGE 9942 CULVER BLVD 1277 CULVER CITY CA 90232 COO 40.00 115385 12199 0 JANA L WELLING 9942 CULVER BLVD 1277 CULVER CITY CA 90232 COMPTROLLER & SR. DI 40.00 235356 67001 0 SARAH VON OLDENBURG 9942 CULVER BLVD 1277 CULVER CITY CA 90232 OPERATIONS AND DIGIT 40.00 119343 20076 0 0 WELLCOME SANGER INSTITUTE WELLCOME GENOME CAMPUS HINXTON CAMBRIDGESHIRE UK CB10 1SA RESEARCH SERVICES 4667353 UNIVERSITY OF CAMBRIDGE C/O BARCLAYS BANK 745 7TH AVENUE NEW YORK NY 10019 RESEARCH SERVICES 3974608 MAKERERE UNIVERSITY BATIVA ROAD OFF GADAFI ROAD KAMPALA UG RESEARCH SERVICES 3891957 KING'S COLLEGE LONDON STRAND LONDON UK WC2R 2LS RESEARCH SERVICES 3535573 REGENTS UNIVERSITY OF CALIFORNIA LOS ANGELES 10889 WILSHIRE BLVD SUITE 600 LOS ANGELES CA 90095 RESEARCH SERVICES 3333260 168 DELTA TISSUE: INTEGRATED PLATFORMS FOR PREDICTING CHANGES IN TISSUE STATE, IS A $55 MILLION EFFORT THAT BRINGS EXPERTS IN THE LIFE SCIENCES AND ENGINEERING TOGETHER FROM ACROSS UNIVERSITIES, FOUNDATIONS, AND THE PRIVATE SECTOR TO DEVELOP A PLATFORM THAT CAN PROFILE TISSUE STATES AND PREDICT TRANSITIONS BETWEEN STATES IN WAYS THAT ARE IMPOSSIBLE TODAY.DELTA TISSUE AIMS TO BUILD NEW PLATFORMS MULTISCALE, MULTIMODAL, AND WIDELY ACCESSIBLE THAT ALLOW US TO PREDICT HOW TISSUES WILL CHANGE IN THE FUTURE WITH THE FIDELITY NEEDED TO INTERVENE IN THE PRESENT A 'TISSUE TIME MACHINE'. 26843344 MULTI-CHANNEL PSYCH (MCPSYCH) AIMS TO DEVELOP AN INTEGRATED MODEL OF ANHEDONIC DEPRESSION THAT CAPTURES BOTH INTERNAL BIOLOGICAL FACTORS AND EXTERNALLY-MANIFESTED, QUANTIFIABLE MEASURES. THE PROGRAM ALSO SEEKS TO REVEAL BIOLOGICAL MECHANISMS OF ANHEDONIA BY SYNCHRONIZING INVESTIGATIONS ACROSS GENES, MOLECULES, CELLS, ANIMAL MODELS, AND HUMANS.MCPSYCH HAS THE GOAL OF DOUBLING THE NUMBER OF PEOPLE WHO RECEIVE AN EFFECTIVE TREATMENT ON THE FIRST TRY. IN ADDITION, THE PROGRAM SEEKS TO REVEAL MECHANISTIC UNDERSTANDING SUFFICIENT TO IDENTIFY EFFECTIVE TREATMENTS FOR HALF OF NON-RESPONSIVE PATIENTS AND HAVE THE SAME IMPACT ON THE SURVIVABILITY OF SEVERE, TREATMENT-RESISTANT DEPRESSION THAT ADVANCES IN DIAGNOSTICS AND TREATMENT HAVE HAD ON THE SURVIVABILITY OF CERTAIN CANCERS. NAMELY, THAT IN THE FUTURE, IT WILL BE POSSIBLE TO HELP 85% OF PEOPLE SURVIVE THEIR SUICIDAL ANHEDONIC DEPRESSION FOR AT LEAST 5 YEARS AND PERHAPS A FULL LIFETIME AFTER DIAGNOSIS. 22746637 THE FIRST 1000 DAYS (1KD) IS A $45 MILLION PROGRAM THAT BRINGS TOGETHER EXPERTS IN THE LIFE SCIENCES, ENGINEERING, AND COMPUTER SCIENCE FROM ACROSS UNIVERSITIES, NONPROFITS, AND THE PRIVATE SECTOR TO DEVELOP SCALABLE MEASUREMENT METHODS AND MODELS TO PREDICT AND PROMOTE HEALTHY BRAIN DEVELOPMENT IN INFANTS.THE FIRST THOUSAND DAYS CAN MAKE ALL THE DIFFERENCE TO A CHILD'S START IN LIFE, PERHAPS MORE SO THAN WE EVER UNDERSTOOD BEFORE. IN THIS EARLY PERIOD, WE DEVELOP CRITICAL COGNITIVE ABILITIES SUCH AS EXECUTIVE FUNCTION (EF) AND SELF-REGULATION. BY THE END OF THE FIRST THOUSAND DAYS, A CHILD'S INDIVIDUAL EF PERFORMANCE CHANGES THEIR ODDS OF DEALING SUCCESSFULLY WITH OPPORTUNITIES AND OBSTACLES THEY FACE IN LIFE. CHILDREN WITH UNDERDEVELOPED EF AT AGE 3 REPRESENT ABOUT 20 PERCENT OF THE POPULATION, BUT MAKE UP NEARLY 80 PERCENT OF ADULTS WHO ARE LIKELY TO REQUIRE SOME FORM OF SOCIETAL OR ECONOMIC ASSISTANCE. 19906053 THE HUMAN ORGANS, PHYSIOLOGY, AND ENGINEERING (HOPE) PROGRAM IS A $50 MILLION EFFORT THAT BRINGS EXPERTS IN THE LIFE SCIENCES AND ENGINEERING TOGETHER FROM ACROSS UNIVERSITIES, FOUNDATIONS, AND COMPANIES TO DEVELOP HUMAN TISSUES, ORGANOIDS, ORGANS, AND PLATFORMS THAT ACCELERATE AND SCALE NEW TREATMENTS.FOCUSED ON REPLICATION OF COMPLEX HUMAN ORGANS AND IMMUNE SYSTEM INTERACTIONS, IF SUCCESSFUL, THE HOPE PROGRAM WOULD HAVE ENORMOUS IMPLICATIONS FOR ADVANCING CANCER, AUTOIMMUNE, AND INFECTIOUS DISEASE INTERVENTIONS, AND, EVENTUALLY, TO BIOENGINEERED, SCALABLY-PRODUCED, IMMUNE-TOLERANT ORGANS FOR TRANSPLANTATION. 19148769 0 0 38649463 0 38649463 0 0 38649463 579742 38069721 1903486 1903486 9795 9795 1893691 0 1893691 0 1893691 170271299 0 170271299 1893691 0 0 1085289 30124518 111958107 143167914 170271299 0 0 0 1893691 168377608 0 0 311545522 0 0 0 0 0 0 0 311545522 1085289 30124518 111958107 168377608 X STRAND THERAPEUTICS INC ONE KENDALL SQUARE BUILDING 200 STE 001 CAMBRIDGE MA 02139 NC FOR USE IN THE DEVELOPMENT OF MRNA TECHNOLOGIES INTENDED TO FACILITATE EXPANDED ACCESS TO LIFE SAVING TREATMENTS 480753 480753 0 14 710850 EXCHANGE GAIN/LOSS 03 4692 0 715542 0 715542 0 0 0 0 0 0 0 0 0 0 X X 1 THE WELLCOME TRUST 215 EUSTON ROAD LONDON ENGLAND UK NW1 2BE 2359904 X ACCOUNTING AND TAX FEES 247402 6185 235850 STRAND THERAPEUTICS INC ONE KENDALL SQUARE BUILDING 200 STE 001 CAMBRIDGE MA 02139 2023-04-19 480753 FOR USE IN THE DEVELOPMENT OF MRNA TECHNOLOGIES INTENDED TO FACILITATE EXPANDED ACCESS TO LIFE SAVING TREATMENTS 480753 NO 06/25/2024 2024-06-25 LEGAL FEES 163437 0 188228 LONG TERM DEPOSITS 107042 86971 86971 BANK CHARGES 28279 0 28279 OFFICE EXPENSES 157023 0 156906 BRAND & VISUAL 444071 0 440365 EXCHANGE GAIN/LOSS 4692 4692 PAYROLL LIABILITIES 94680 67349 ACCRUED LIABILITIES 2107797 7966823 STRATEGY, ANALYTICS, & COMMUNICATIONS 897038 0 918648 WEBSITE DEVELOPMENT & MAINTENANCE 162339 0 150270 PAYROLL PROCESSING FEES 114415 0 114415 CONSULTING FEES 633396 0 625271 PROGRAMS - RESEARCH AND DEVELOPMENT SERVICES 147435256 0 159209043 STATE TAXES 1000 0 1000 PAYROLL TAXES 204801 0 204801