2024-02-11T22:57:31-07:00 2022-12-31 990 2022-01-01 823762441 CANINE CANCER RESEARCH ALLIANCE CANI 4254664453 PO Box 385 Bellevue WA 98009 Mari Whitaker Director 4254664453 2024-01-05 Mari Whitaker 999009999 1 1 11 1 AAL2 X 2022 2023-04-26 12:10:37Z Canine Cancer Alliance Mari Maeda Whitaker 13440 NE 29th Pl Bellevue WA 98005 415845 0 X https://www.ccralliance.org/ X 2017 WA The mission of the Canine Cancer Alliance is to end dog cancer as we know it today by funding and advancing research for prevention and cures. Studies and clinical trials supported by the CCA emphasize the discovery and development of safe, effective, and affordable treatments for our canine family members. 7 7 0 6 0 0 127027 413227 0 0 14 2618 0 0 127041 415845 86810 183884 0 0 0 0 0 0 6818 15033 28031 101843 211915 25198 203930 166928 370858 0 0 166928 370858 The mission of the Canine Cancer Alliance is to end dog cancer as we know it today by funding and advancing research for prevention, early detection and cures. Studies and clinical trials supported by the CCA emphasize the development of safe, effective, and affordable treatments for canine patients. 0 0 202282 183884 0 2022 program focused on cancer immunotherapy research. Research Studies. Two new studies were initiated: (1)CAR-T therapy for sarcomas (University of Illinois with Northwestern University) (2) Immunotherapy for transitional cell carcinoma (bladder cancer) and BRAF monitoring (North Carolina State University). Two other studies are ongoing: clinical studies in therapeutic canine cancer vaccine targeting EGFR/HER2 over-expressing tumors (Yale School of Medicine) and nonspecific cancer vaccine immunotherapy. EGFR/HER2 vaccine clinical trial was opened in Nov 2022 and began enrolling patients with osteosarcoma, hemangiosarcoma and TCC. Education and cancer awareness. We developed and shared information including videos to advance canine cancer awareness on our website and social media channels. The content includes details of new cancer treatments including cancer immunotherapy, clinical trials, recent research results, and strategies for reducing cancer risks and early detection. 0 0 0 202282 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 X 7 7 0 0 0 0 0 0 0 1 1 0 0 1 1 0 1 0 0 0 0 0 X X X Mari Whitaker 4254664453 13440 NE 29th l Bellevue WA 98005 Mari Maeda Whitaker Director, Officer 40 X X 0 0 0 Tai Truong Director 0.5 X 0 0 0 Sri Kumar Director 0.5 0 X 0 0 0 Sam Earp Director 0.5 0 X 0 0 0 Elizabeth Zuidema Director 0.5 0 X 0 0 0 James Gimlett Director 2 0 X 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413227 210478 413227 0 0 0 0 0 2618 2618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415845 2618 0 0 183884 183884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10214 10049 165 0 90 0 90 0 56 0 56 0 0 0 0 0 0 0 0 0 1565 140 29 1396 6880 3580 899 2401 491 199 292 2933 1433 433 1067 0 0 0 0 0 0 0 0 89 89 0 0 0 0 0 0 1760 1760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944 0 944 0 Permit fees 1662 0 0 1662 Video editing service 1347 1347 0 0 211915 202282 2815 6818 0 0 166928 370858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166928 370858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 X 166928 370858 0 0 166928 370858 166928 370858 203930 0 0 0 0 0 X 0 0 0 X 27740 101062 102729 127013 413227 771771 27740 101062 102729 127013 413227 771771 263978 507793 0 716 89 14 2618 3437 0 0 0 0 775208 0.65504 0.98 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 1 Yale University School of Medicine 333 Cedar St New Haven CT 06510 060646973 90000 Research grant to develop safe and effective cancer immunotherapy. Determine the efficacy of EGFR/HER2 canine cancer vaccine through a clinical trial with canine patients. Explore strategies to enhance the patient response rate. University of Illinois Foundation 1305 W Green St Urbana IL 61801 376006007 46400 The grant is to investigate the safety and efficacy of CAR-T therapy for dogs with aggressive sarcomas. Clinical trial will enrol dogs with hemangiosarcoma, osteosarcoma and recurrent soft tissue sarcoma. North Carolina University Veterinary Medical Foundation 1060 William Moore Dr Raleigh NC 27607 566000756 35484 This grant will determine the efficacy of canine cancer immunotherapy treatment for dogs with transitional cell carcinoma (TCC). Patients with bladder cancer with BRAF positive mutation will be enrolled and monitored with molecular tests (urine tests) for cancer progression. Therajan LLC 290 Congress Ave New Haven CT 06519 873925220 12000 This grant supports clinical trial, regulatory approval and commercialization of new canine cancer immunotherapy for dogs with solid tumors. 3 1 Schedule I, Part I, Line 2 Canine Cancer Alliance's program management team holds regular meetings to review the status of each project with every grantee for the duration of the project. The review covers scientific progress as well as the financial status of the project. The grantees also submit an annual summary of progress to the CCA. Form 990, Part VI, Section B, Line 11b The draft Form 990 is provided to each board member for full review before filing. Form 990, Part VI, Section B, Line 12c Prior to proposal and project review, board members and key members who may become involved in the review are required to submit information about any positions or holdings that have potential conflicts of interest. This information is reviewed by the COI committee for the member's suitability to be involved in reviewing or managing the project. The review will determine whether the member will be asked to recuse himself or herself from the proposal or project. Form 990, Part VI, Section C, Line 19 All public documents are made available upon request sent to the organization's physical address or requested by email, or on the website. Canine Cancer Alliance is an all-volunteer organization and has in past relied on volunteers for tax-filing. Unfortunately, the volunteer we were relying on to file Form 990 stopped working with our organization right before the Nov 15 extension due date. I stepped in to complete the form, but I had health issues and could not complete the form in December or January. We learned an important lesson from this process and in future, we plan to hire a professional to file Form 990 and to start the process well before the deadline. We wanted to maximize the funds for canine cancer research grants, hence we were trying to minimize spending on contractors.