2024-05-15T14:23:37-04:00 2023-12-31 272004914 EDWARD L ARCARA CPA PC 465 FRANKLIN ST BUFFALO NY 142021301 990EZ 2023-01-01 201959386 CHIARI & SYRINGOMYELIA RESEARCH FOUNDATION INC CHIA 7166337022 228 GARRY DRIVE WEST SENECA NY 14224 MARK S KANE PRESIDENT 7166337022 2024-05-02 true MARK KANE 999009999 false EDWARD L ARCARA CPA P00331796 7168842492 2024-05-13 2023 2023-04-26 12:10:37Z X X WWW.COLUMNOFHOPE.ORG X X 12502 X 11776 726 12502 57767 57767 -45265 336876 291611 336876 291611 336876 291611 336876 291611 X SEARCHING FOR BETTER UNDERSTANDING, TREATMENTS AND CURES FOR CHIARI MALFORMATION (CM), SYRINGOMYELIA (SM), NEUROPATHIC PAIN AND RELATED DISORDERS INVESTIGATION OF THE DEVELOPMENT AND POSSIBLE TREATMENT OF CHIARI MALFORMATION. ONGOING STUDIES: PATHOPHYSIOLOGY AND TREATMENT OF CHIARI MALFORMATION AND SYRINGOMYELIA - AUSTRALIA IDENTIFYING CHANGES IN COGNITION AND PAIN NETWORKS IN CHIARI PATIENTS (USING FMRI) - WISCONSIN US - COSPONSORING SUPPORTING LARGER GOVERNMENT SPONSORED STUDY BY SPONSORING EXPERTS NOT FULLY FUNDED BY THE STUDY. CHIARI MALFORMATION: DEFINING PATHOPHYSIOLOGY & TREATMENT GOALS RECENT PUBLICATIONS: CEREBELLAR TONSILLAR DESCENT MIMICKING CHIARI MALFORMATION - JOURNAL OF CLINICAL MEDICINE APRIL 2023 X 56822 UNDERSTANDING THE BIOLOGY, CHEMISTRY, AND FLUID DYNAMICS OF POST TRAUMATIC SYRINGOMYELIA TO UNDERSTAND ALL FORMS OF SYRINGOMYELIA. RECENT PUBLICATIONS: A NOVEL METHOD TO QUANTIFY PERIVASCULAR SPACE ENLARGEMENT NEAR THE SYRINX IN A RODENT MODEL OF POST-TRAUMATIC SYRINGOMYELIA - NATURE.COM - SCIENTIFIC REPORTS - 2023 AQUAPORIN-4 EXPRESSION AND MODULATION IN A RAT MODEL OF POST-TRAUMATIC SYRINGOMYELIA NATURE.COM SCIENTIFIC REPORTS - JUNE 2023 INVESTIGATING POST-TRAUMATIC SYRINGOMYELIA AND LOCAL FLUID OSMOREGULATION VIA A RAT MODEL FLUIDS & BARRIERS OF THE CNS - FEB 2024 OSMOTIC CONTRIBUTION OF SYNTHESIZED BETAINE BY CHOLINE DEHYDROGENASE USING IN VIVO AND IN VITRO MODELS OF POST-TRAUMATIC SYRINGOMYELIA CELLULAR AND MOLECULAR BIOENGINEERING APRIL COMMITMENTS: 30,055 IS THE REMAINING COMMITMENT ON AN UNFINISHED GRANT CURRENT PLANS INCLUDE: A)TAKING PRELIMINARY POSITIVE SURGICAL RESULTS TREATING CHIARI HEADACHE, COGNITIVE IMPACTS, AND RESOLUTION OF SYRINGOMYELIA AND DETERMINING THE BEST STUDY DESIGN TO CONFIRM THOSE RESULTS. B)DETERMINING THE NEXT STEPS IN RESOLVING SYRINGOMYELIA, USING THE POST TRAUMATIC SYRINGOMYELIA MODELS AND THE CHARI SURGERY STUDY RESULTS. 56822 MARK S KANE PRESIDENT 8.00 0 BARBARA KANE SECRETARY 1.00 0 KEVIN STRINGER VICE PRESIDE 1.00 0 JEFF MILLER TREASURER 1.00 0 LAURA HOLENA DIRECTOR 1.00 0 false false false false false false false false false NY MARK S KANE 228 GARRY DRIVE WEST SENECA NY 14224 7166337022 false false false false false false false false false false false NONE NONE true X 108389 51454 47641 18819 11776 238079 108389 51454 47641 18819 11776 238079 92380 145699 231 77 308 238387 85687 0.61120 0.71650 X FORM 990-EZ, PART I FORM 990-EZ, PART I, LINE 8 MEDICAL RESEARCH CONFERENCE REVENUE FORM 990-EZ, PART I, LINE 16 EXPENSES OTHER ADMINISTRATIVE EXP 945 RESEARCH GRANTS 56,822 TOTAL 57,767 FORM 990-EZ, PART III SEARCHING FOR BETTER UNDERSTANDING, TREATMENTS AND CURES FOR CHIARI MALFORMATION (CM), SYRINGOMYELIA (SM), NEUROPATHIC PAIN AND RELATED DISORDERS FORM 990-EZ, PART III, LINE 28 INVESTIGATION OF THE DEVELOPMENT AND POSSIBLE TREATMENT OF CHIARI MALFORMATION. ONGOING STUDIES: PATHOPHYSIOLOGY AND TREATMENT OF CHIARI MALFORMATION AND SYRINGOMYELIA - AUSTRALIA IDENTIFYING CHANGES IN COGNITION AND PAIN NETWORKS IN CHIARI PATIENTS (USING FMRI) - WISCONSIN US - COSPONSORING SUPPORTING LARGER GOVERNMENT SPONSORED STUDY BY SPONSORING EXPERTS NOT FULLY FUNDED BY THE STUDY. CHIARI MALFORMATION: DEFINING PATHOPHYSIOLOGY & TREATMENT GOALS RECENT PUBLICATIONS: CEREBELLAR TONSILLAR DESCENT MIMICKING CHIARI MALFORMATION - JOURNAL OF CLINICAL MEDICINE APRIL 2023 FORM 990-EZ, PART III, LINE 29 UNDERSTANDING THE BIOLOGY, CHEMISTRY, AND FLUID DYNAMICS OF POST TRAUMATIC SYRINGOMYELIA TO UNDERSTAND ALL FORMS OF SYRINGOMYELIA. RECENT PUBLICATIONS: A NOVEL METHOD TO QUANTIFY PERIVASCULAR SPACE ENLARGEMENT NEAR THE SYRINX IN A RODENT MODEL OF POST-TRAUMATIC SYRINGOMYELIA - NATURE.COM - SCIENTIFIC REPORTS - 2023 AQUAPORIN-4 EXPRESSION AND MODULATION IN A RAT MODEL OF POST-TRAUMATIC SYRINGOMYELIA NATURE.COM SCIENTIFIC REPORTS - JUNE 2023 INVESTIGATING POST-TRAUMATIC SYRINGOMYELIA AND LOCAL FLUID OSMOREGULATION VIA A RAT MODEL FLUIDS & BARRIERS OF THE CNS - FEB 2024 OSMOTIC CONTRIBUTION OF SYNTHESIZED BETAINE BY CHOLINE DEHYDROGENASE USING IN VIVO AND IN VITRO MODELS OF POST-TRAUMATIC SYRINGOMYELIA CELLULAR AND MOLECULAR BIOENGINEERING APRIL COMMITMENTS: 30,055 IS THE REMAINING COMMITMENT ON AN UNFINISHED GRANT CURRENT PLANS INCLUDE: A)TAKING PRELIMINARY POSITIVE SURGICAL RESULTS TREATING CHIARI HEADACHE, COGNITIVE IMPACTS, AND RESOLUTION OF SYRINGOMYELIA AND DETERMINING THE BEST STUDY DESIGN TO CONFIRM THOSE RESULTS. B)DETERMINING THE NEXT STEPS IN RESOLVING SYRINGOMYELIA, USING THE POST TRAUMATIC SYRINGOMYELIA MODELS AND THE CHARI SURGERY STUDY RESULTS.